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Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl

The purpose of the study was to report a unique case of Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl. A 16-year-old girl presented with decreased vision in the right eye preceding an episode of fever with a rash associated with burning micturition. The patient was exami...

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Autores principales: Dhiman, Richa, Sharma, Nancy, Chauhan, Jyoti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220441/
https://www.ncbi.nlm.nih.gov/pubmed/37252173
http://dx.doi.org/10.4103/tjo.TJO-D-22-00101
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author Dhiman, Richa
Sharma, Nancy
Chauhan, Jyoti
author_facet Dhiman, Richa
Sharma, Nancy
Chauhan, Jyoti
author_sort Dhiman, Richa
collection PubMed
description The purpose of the study was to report a unique case of Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl. A 16-year-old girl presented with decreased vision in the right eye preceding an episode of fever with a rash associated with burning micturition. The patient was examined after taking appropriate consent. The slit-lamp examination revealed a ring-shaped corneal infiltrate with an epithelial defect in her right eye. Corneal scrapings were sent for microbiological evaluation which revealed Gram-negative rods and culture identified it as extended-spectrum beta-lactamase-producing Klebsiella pneumoniae colonies. The patient showed a good response to topical fortified amikacin and tobramycin. For her systemic complaints, the pediatrician did a thorough investigative workup out of which blood culture showed growth of K. pneumoniae. Hence, intravenous antibiotics were given based on the antibiogram report and the patient recovered. After 2 weeks, a paracentral infiltrate in her left eye was noted followed by anterior uveitis. The patient responded well to the topical course of steroids along with aminoglycosides. Four months later, she had a recurrence of anterior uveitis in the right eye preceded by fever. Blood investigations were negative. Hence, a diagnosis of recurrent uveitis secondary to endogenous infection was made and the patient was successfully treated with a short course of topical steroids. The patient is on follow-up for the past 6 months and maintaining the best-corrected visual acuity of 20/20 OU with normal intraocular pressure and quiet anterior chamber (AC). This is the first clinical report describing a ring infiltrate in endogenous Klebsiella keratitis and emphasizes thorough workup for prompt treatment.
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spelling pubmed-102204412023-05-28 Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl Dhiman, Richa Sharma, Nancy Chauhan, Jyoti Taiwan J Ophthalmol Case Report The purpose of the study was to report a unique case of Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl. A 16-year-old girl presented with decreased vision in the right eye preceding an episode of fever with a rash associated with burning micturition. The patient was examined after taking appropriate consent. The slit-lamp examination revealed a ring-shaped corneal infiltrate with an epithelial defect in her right eye. Corneal scrapings were sent for microbiological evaluation which revealed Gram-negative rods and culture identified it as extended-spectrum beta-lactamase-producing Klebsiella pneumoniae colonies. The patient showed a good response to topical fortified amikacin and tobramycin. For her systemic complaints, the pediatrician did a thorough investigative workup out of which blood culture showed growth of K. pneumoniae. Hence, intravenous antibiotics were given based on the antibiogram report and the patient recovered. After 2 weeks, a paracentral infiltrate in her left eye was noted followed by anterior uveitis. The patient responded well to the topical course of steroids along with aminoglycosides. Four months later, she had a recurrence of anterior uveitis in the right eye preceded by fever. Blood investigations were negative. Hence, a diagnosis of recurrent uveitis secondary to endogenous infection was made and the patient was successfully treated with a short course of topical steroids. The patient is on follow-up for the past 6 months and maintaining the best-corrected visual acuity of 20/20 OU with normal intraocular pressure and quiet anterior chamber (AC). This is the first clinical report describing a ring infiltrate in endogenous Klebsiella keratitis and emphasizes thorough workup for prompt treatment. Wolters Kluwer - Medknow 2023-01-05 /pmc/articles/PMC10220441/ /pubmed/37252173 http://dx.doi.org/10.4103/tjo.TJO-D-22-00101 Text en Copyright: © 2023 Taiwan Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Dhiman, Richa
Sharma, Nancy
Chauhan, Jyoti
Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl
title Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl
title_full Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl
title_fullStr Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl
title_full_unstemmed Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl
title_short Klebsiella keratitis presenting as a ring infiltrate in an adolescent girl
title_sort klebsiella keratitis presenting as a ring infiltrate in an adolescent girl
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220441/
https://www.ncbi.nlm.nih.gov/pubmed/37252173
http://dx.doi.org/10.4103/tjo.TJO-D-22-00101
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