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Dry eye disease: A review of anti-inflammatory therapies
Dry eye disease (DED) is a common chronic ocular disease. DED can have a significant impact on visual function, causing disturbances to comfort, daily activities, and general quality of life. The varied nature of DED makes it difficult to point to a specific cause of the syndrome. However, current l...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220443/ https://www.ncbi.nlm.nih.gov/pubmed/37252177 http://dx.doi.org/10.4103/2211-5056.369606 |
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author | Nguyen, Annie Kolluru, Ajay Beglarian, Talia |
author_facet | Nguyen, Annie Kolluru, Ajay Beglarian, Talia |
author_sort | Nguyen, Annie |
collection | PubMed |
description | Dry eye disease (DED) is a common chronic ocular disease. DED can have a significant impact on visual function, causing disturbances to comfort, daily activities, and general quality of life. The varied nature of DED makes it difficult to point to a specific cause of the syndrome. However, current literature agrees that the inflammation of the cornea and conjunctiva plays a major role in its pathogenesis. Therapies targeted toward inflammation have shown varied success in the treatment of DED. The purpose of this review is to provide an overview of the prevalence and inflammatory pathophysiology of DED and discussion of the available anti-inflammatory therapies including the following: Nonsteroidal anti-inflammatory drugs, corticosteroids, and other hormonal therapies, nonsteroidal immunomodulators, biological tear replacement, antibiotics, dietary supplements, tea tree oil, and intense pulsed light. |
format | Online Article Text |
id | pubmed-10220443 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-102204432023-05-28 Dry eye disease: A review of anti-inflammatory therapies Nguyen, Annie Kolluru, Ajay Beglarian, Talia Taiwan J Ophthalmol Review Article Dry eye disease (DED) is a common chronic ocular disease. DED can have a significant impact on visual function, causing disturbances to comfort, daily activities, and general quality of life. The varied nature of DED makes it difficult to point to a specific cause of the syndrome. However, current literature agrees that the inflammation of the cornea and conjunctiva plays a major role in its pathogenesis. Therapies targeted toward inflammation have shown varied success in the treatment of DED. The purpose of this review is to provide an overview of the prevalence and inflammatory pathophysiology of DED and discussion of the available anti-inflammatory therapies including the following: Nonsteroidal anti-inflammatory drugs, corticosteroids, and other hormonal therapies, nonsteroidal immunomodulators, biological tear replacement, antibiotics, dietary supplements, tea tree oil, and intense pulsed light. Wolters Kluwer - Medknow 2023-02-13 /pmc/articles/PMC10220443/ /pubmed/37252177 http://dx.doi.org/10.4103/2211-5056.369606 Text en Copyright: © 2023 Taiwan Journal of Ophthalmology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Nguyen, Annie Kolluru, Ajay Beglarian, Talia Dry eye disease: A review of anti-inflammatory therapies |
title | Dry eye disease: A review of anti-inflammatory therapies |
title_full | Dry eye disease: A review of anti-inflammatory therapies |
title_fullStr | Dry eye disease: A review of anti-inflammatory therapies |
title_full_unstemmed | Dry eye disease: A review of anti-inflammatory therapies |
title_short | Dry eye disease: A review of anti-inflammatory therapies |
title_sort | dry eye disease: a review of anti-inflammatory therapies |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220443/ https://www.ncbi.nlm.nih.gov/pubmed/37252177 http://dx.doi.org/10.4103/2211-5056.369606 |
work_keys_str_mv | AT nguyenannie dryeyediseaseareviewofantiinflammatorytherapies AT kolluruajay dryeyediseaseareviewofantiinflammatorytherapies AT beglariantalia dryeyediseaseareviewofantiinflammatorytherapies |