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Early-life propofol exposure does not affect later-life GABAergic inhibition, seizure induction, or social behavior

The early developing brain is especially vulnerable to anesthesia, which can result in long lasting functional changes. We examined the effects of early-life propofol on adult excitatory-inhibitory balance and behavior. Postnatal day 7 male mice were exposed to propofol (250 mg/kg i.p.) and anesthes...

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Detalles Bibliográficos
Autores principales: Liu, Jinyang, Lin, Daisy, Yau, Alice, Cottrell, James E., Kass, Ira S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220478/
https://www.ncbi.nlm.nih.gov/pubmed/37252630
http://dx.doi.org/10.1016/j.ibneur.2023.05.007