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Evaluation and Determination of a Suitable Passage Number of Codon Pair Deoptimized PRRSV-1 Vaccine Candidate in Pigs

Porcine reproductive and respiratory syndrome virus (PRRSV) is major economic problem given its effects on swine health and productivity. Therefore, we evaluated the genetic stability of a codon pair de-optimized (CPD) PRRSV, E38-ORF7 CPD, as well as the master seed passage threshold that elicited a...

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Detalles Bibliográficos
Autores principales: Lee, Min-A, You, Su-Hwa, Jayaramaiah, Usharani, Shin, Eun-Gyeong, Song, Seung-Min, Ju, Lanjeong, Kang, Seok-Jin, Cho, Sun-Hee, Hyun, Bang-Hun, Lee, Hyang-Sim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220689/
https://www.ncbi.nlm.nih.gov/pubmed/37243157
http://dx.doi.org/10.3390/v15051071