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Association between Fluoxetine Use and Overall Survival among Patients with Cancer Treated with PD-1/L1 Immunotherapy

Checkpoint inhibitors can be a highly effective antitumor therapy but only to a subset of patients, presumably due to immunotherapy resistance. Fluoxetine was recently revealed to inhibit the NLRP3 inflammasome, and NLRP3 inhibition could serve as a target for immunotherapy resistance. Therefore, we...

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Detalles Bibliográficos
Autores principales:	Magagnoli, Joseph, Narendran, Siddharth, Pereira, Felipe, Cummings, Tammy H., Hardin, James W., Sutton, S. Scott, Ambati, Jayakrishna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220705/ https://www.ncbi.nlm.nih.gov/pubmed/37242422 http://dx.doi.org/10.3390/ph16050640

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