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Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients
Fungal infections are a significant source of morbidity in the lung transplant population via direct allograft damage and predisposing patients to the development of chronic lung allograft dysfunction. Prompt diagnosis and treatment are imperative to limit allograft damage. This review article discu...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220796/ https://www.ncbi.nlm.nih.gov/pubmed/37242364 http://dx.doi.org/10.3390/pathogens12050694 |
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author | Escamilla, Jesus E. January, Spenser E. Vazquez Guillamet, Rodrigo |
author_facet | Escamilla, Jesus E. January, Spenser E. Vazquez Guillamet, Rodrigo |
author_sort | Escamilla, Jesus E. |
collection | PubMed |
description | Fungal infections are a significant source of morbidity in the lung transplant population via direct allograft damage and predisposing patients to the development of chronic lung allograft dysfunction. Prompt diagnosis and treatment are imperative to limit allograft damage. This review article discusses incidence, risk factors, and symptoms with a specific focus on diagnostic and treatment strategies in the lung transplant population for fungal infections caused by Aspergillus, Candida, Coccidioides, Histoplasma, Blastomyces, Scedosporium/Lomentospora, Fusarium, and Pneumocystis jirovecii. Evidence for the use of newer triazole and inhaled antifungals to treat isolated pulmonary fungal infections in lung transplant recipients is also discussed. |
format | Online Article Text |
id | pubmed-10220796 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102207962023-05-28 Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients Escamilla, Jesus E. January, Spenser E. Vazquez Guillamet, Rodrigo Pathogens Review Fungal infections are a significant source of morbidity in the lung transplant population via direct allograft damage and predisposing patients to the development of chronic lung allograft dysfunction. Prompt diagnosis and treatment are imperative to limit allograft damage. This review article discusses incidence, risk factors, and symptoms with a specific focus on diagnostic and treatment strategies in the lung transplant population for fungal infections caused by Aspergillus, Candida, Coccidioides, Histoplasma, Blastomyces, Scedosporium/Lomentospora, Fusarium, and Pneumocystis jirovecii. Evidence for the use of newer triazole and inhaled antifungals to treat isolated pulmonary fungal infections in lung transplant recipients is also discussed. MDPI 2023-05-10 /pmc/articles/PMC10220796/ /pubmed/37242364 http://dx.doi.org/10.3390/pathogens12050694 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Escamilla, Jesus E. January, Spenser E. Vazquez Guillamet, Rodrigo Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients |
title | Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients |
title_full | Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients |
title_fullStr | Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients |
title_full_unstemmed | Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients |
title_short | Diagnosis and Treatment of Fungal Infections in Lung Transplant Recipients |
title_sort | diagnosis and treatment of fungal infections in lung transplant recipients |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220796/ https://www.ncbi.nlm.nih.gov/pubmed/37242364 http://dx.doi.org/10.3390/pathogens12050694 |
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