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Novel Adjuvant S-540956 Targets Lymph Nodes and Reduces Genital Recurrences and Vaginal Shedding of HSV-2 DNA When Administered with HSV-2 Glycoprotein D as a Therapeutic Vaccine in Guinea Pigs

Herpes simplex virus type 2 (HSV-2) is a leading cause of genital ulcer disease and a major risk factor for acquisition and transmission of HIV. Frequent recurrent genital lesions and concerns about transmitting infection to intimate partners affect the quality of life of infected individuals. Thera...

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Detalles Bibliográficos
Autores principales:	Awasthi, Sita, Onishi, Motoyasu, Lubinski, John M., Fowler, Bernard T., Naughton, Alexis M., Hook, Lauren M., Egan, Kevin P., Hagiwara, Masaki, Shirai, Seiki, Sakai, Akiho, Nakagawa, Takayuki, Goto, Kumiko, Yoshida, Osamu, Stephens, Alisa J., Choi, Grace, Cohen, Gary H., Katayama, Kazufumi, Friedman, Harvey M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220834/ https://www.ncbi.nlm.nih.gov/pubmed/37243234 http://dx.doi.org/10.3390/v15051148

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