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Exposure–Response Analysis of the Sodium–Glucose Cotransporter-2 Inhibitors Dapagliflozin and Empagliflozin on Kidney Hemodynamics in Patients with Type 2 Diabetes
Sodium–glucose cotransporter-2 (SGLT2) inhibitors improve markers for renal and cardiovascular outcomes in patients with and without type 2 diabetes (T2D). To assess whether individual differences in plasma drug exposure can explain inter-individual response variation, we characterized the exposure–...
Autores principales: | van der Hoek, Sjoukje, Koomen, Jeroen V., van Bommel, Erik J. M., Mosterd, Charlotte M., Scholtes, Rosalie A., Hesp, Anne C., Stevens, Jasper, van Raalte, Daniel H., Heerspink, Hiddo J. L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220852/ https://www.ncbi.nlm.nih.gov/pubmed/37240917 http://dx.doi.org/10.3390/jpm13050747 |
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