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Relating Molecular Dynamics Simulations to Functional Activity for Gly-Rich Membranolytic Helical Kiadin Peptides

Kiadins are in silico designed peptides with a strong similarity to diPGLa-H, a tandem sequence of PGLa-H (KIAKVALKAL) and with single, double or quadruple glycine substitutions. They were found to show high variability in their activity and selectivity against Gram-negative and Gram-positive bacter...

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Detalles Bibliográficos
Autores principales:	Rončević, Tomislav, Maleš, Matko, Sonavane, Yogesh, Guida, Filomena, Pacor, Sabrina, Tossi, Alessandro, Zoranić, Larisa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220883/ https://www.ncbi.nlm.nih.gov/pubmed/37242675 http://dx.doi.org/10.3390/pharmaceutics15051433

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