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Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery

Extracellular vesicles (ECVs) have been abandoned as bio-inspired drug delivery systems (DDS) in the biomedical field. ECVs have a natural ability to cross over extracellular and intracellular barriers, making them superior to manufactured nanoparticles. Additionally, they have the ability to move b...

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Detalles Bibliográficos
Autores principales: Ashique, Sumel, Anand, Krishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220982/
https://www.ncbi.nlm.nih.gov/pubmed/37242668
http://dx.doi.org/10.3390/pharmaceutics15051426
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author Ashique, Sumel
Anand, Krishnan
author_facet Ashique, Sumel
Anand, Krishnan
author_sort Ashique, Sumel
collection PubMed
description Extracellular vesicles (ECVs) have been abandoned as bio-inspired drug delivery systems (DDS) in the biomedical field. ECVs have a natural ability to cross over extracellular and intracellular barriers, making them superior to manufactured nanoparticles. Additionally, they have the ability to move beneficial biomolecules among far-flung bodily cells. These advantages and the accomplishment of favorable in vivo results convincingly show the value of ECVs in medication delivery. The usage of ECVs is constantly being improved, as it might be difficult to develop a consistent biochemical strategy that is in line with their useful clinical therapeutic uses. Extracellular vesicles (ECVs) have the potential to enhance the therapy of diseases. Imaging technologies, particularly radiolabelled imaging, have been exploited for non-invasive tracking to better understand their in vivo activity.
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spelling pubmed-102209822023-05-28 Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery Ashique, Sumel Anand, Krishnan Pharmaceutics Review Extracellular vesicles (ECVs) have been abandoned as bio-inspired drug delivery systems (DDS) in the biomedical field. ECVs have a natural ability to cross over extracellular and intracellular barriers, making them superior to manufactured nanoparticles. Additionally, they have the ability to move beneficial biomolecules among far-flung bodily cells. These advantages and the accomplishment of favorable in vivo results convincingly show the value of ECVs in medication delivery. The usage of ECVs is constantly being improved, as it might be difficult to develop a consistent biochemical strategy that is in line with their useful clinical therapeutic uses. Extracellular vesicles (ECVs) have the potential to enhance the therapy of diseases. Imaging technologies, particularly radiolabelled imaging, have been exploited for non-invasive tracking to better understand their in vivo activity. MDPI 2023-05-06 /pmc/articles/PMC10220982/ /pubmed/37242668 http://dx.doi.org/10.3390/pharmaceutics15051426 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ashique, Sumel
Anand, Krishnan
Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery
title Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery
title_full Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery
title_fullStr Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery
title_full_unstemmed Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery
title_short Radiolabelled Extracellular Vesicles as Imaging Modalities for Precise Targeted Drug Delivery
title_sort radiolabelled extracellular vesicles as imaging modalities for precise targeted drug delivery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10220982/
https://www.ncbi.nlm.nih.gov/pubmed/37242668
http://dx.doi.org/10.3390/pharmaceutics15051426
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