Cargando…

Synthesis of New Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via an Ugi-Zhu/Cascade/Click Strategy

A diversity-oriented synthesis (DOS) of two new polyheterocyclic compounds was performed via an Ugi-Zhu/cascade (N-acylation/aza Diels-Alder cycloaddition/decarboxylation/dehydration)/click strategy, both step-by-step to optimize all involved experimental stages, and in one pot manner to evaluate th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Blanco-Carapia, Roberto E., Aguilar-Rangel, Enrique A., Rincón-Guevara, Mónica A., Islas-Jácome, Alejandro, González-Zamora, Eduardo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221234/ https://www.ncbi.nlm.nih.gov/pubmed/37241828 http://dx.doi.org/10.3390/molecules28104087

Ejemplares similares

Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Ugi–Zhu Reaction and In Vitro–In Silico Studies against Breast Carcinoma
por: Morales-Salazar, Ivette, et al.
Publicado: (2023)

Synthesis of Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via a One-Pot (Ugi-3CR/aza Diels-Alder/N-acylation/aromatization/S(N)2) Process. A Suitable Alternative towards Novel Aza-Analogues of Falipamil
por: Zamudio-Medina, Angel, et al.
Publicado: (2018)

Synthesis of New 5-Aryl-benzo[f][1,7]naphthyridines via a Cascade Process (Ugi-3CR/Intramolecular Aza-Diels-Alder Cycloaddition)/Aromatization
por: Vázquez-Vera, Óscar, et al.
Publicado: (2018)

Free-radical cyclization approach to polyheterocycles containing pyrrole and pyridine rings
por: Mosiagin, Ivan P, et al.
Publicado: (2021)

An Overview of the Biological Activity of Pyrrolo[3,4-c]pyridine Derivatives
por: Wójcicka, Anna, et al.
Publicado: (2021)

Synthesis of Pyrrolo[3,4-b]pyridin-5-ones via Multicomponent Reactions and In Vitro–In Silico Studies Against SiHa, HeLa, and CaSki Human Cervical Carcinoma Cell Lines
por: Segura-Olvera, Daniel, et al.
Publicado: (2019)

Diversified Synthesis of Chiral Chromane-Containing Polyheterocyclic Compounds via Asymmetric Organocatalytic Cascade Reactions
por: Chen, Ying-Han, et al.
Publicado: (2018)

Copper-Catalyzed Modular Assembly of Polyheterocycles
por: Wang, Qian, et al.
Publicado: (2020)

6,6′-(Pyridine-2,6-diyl)bis(pyrrolo[3,4-b]pyridine-5,7-dione)
por: Van der Berg, P. C. W., et al.
Publicado: (2011)

Bottleneck Effect Explained by Le Bail Refinements: Structure Transformation of Mg-CUK-1 by Confining H(2)O Molecules
por: Sánchez-González, Elí, et al.
Publicado: (2020)

Synthesis of Polyheterocyclic Dimers Containing Restricted and Constrained Peptidomimetics via IMCR-Based Domino/Double CuAAC Click Strategy
por: Pharande, Shrikant G., et al.
Publicado: (2020)

Ugi post-condensation copper-triggered oxidative cascade towards pyrazoles
por: Santos, Aurélie Dos, et al.
Publicado: (2011)

An Easy Access to Furan-Fused Polyheterocyclic Systems
por: Benzi, Alice, et al.
Publicado: (2022)

Bioresearch of New 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones
por: Szkatuła, Dominika, et al.
Publicado: (2020)

Complex Polyheterocycles and the Stereochemical Reassignment of Pileamartine A via Aza-Heck Triggered Aryl C–H Functionalization Cascades
por: Jones, Benjamin T., et al.
Publicado: (2021)

6-Benzyl-6,7-dihydro-5H-pyrrolo[3,4-b]pyridine-5,7-dione
por: Sun, Hong-Shun, et al.
Publicado: (2011)

Nature of Linear Spectral Properties and Fast Electronic Relaxations in Green Fluorescent Pyrrolo[3,4-c]Pyridine Derivative
por: Bashmakova, Nataliia V., et al.
Publicado: (2021)

Synthesis and Antiproliferative Activity of Thiazolyl-bis-pyrrolo[2,3-b]pyridines and Indolyl-thiazolyl-pyrrolo[2,3-c]pyridines, Nortopsentin Analogues
por: Carbone, Anna, et al.
Publicado: (2015)

2-(1H-Pyrrolo[2,3-b]pyridin-2-yl)pyridine
por: Huang, Ping-Hsin, et al.
Publicado: (2012)

4-(1H-Pyrrolo[2,3-b]pyridin-2-yl)pyridine
por: Huang, Ping-Hsin, et al.
Publicado: (2013)

Synthesis of Novel bis-1,5-Disubstituted-1H-Tetrazoles by an Efficient Catalyst-Free Ugi-Azide Repetitive Process
por: Cárdenas-Galindo, Luís E., et al.
Publicado: (2015)

Old Master Zhu: in memory of virologist Guan-Fu Zhu
por: Ye, Qing, et al.
Publicado: (2017)

Complexity-Building ESIPT-Assisted Synthesis of Fused Polyheterocyclic Sulfonamides
por: Beduru, Srinivas, et al.
Publicado: (2023)

Rhodium catalyzed cascade cyclization featuring B–H and C–H activation: one-step construction of carborane-fused N-polyheterocycles
por: Lyu, Hairong, et al.
Publicado: (2018)

Synthesis of Chromeno[3,4-b]piperazines by an Enol-Ugi/Reduction/Cyclization Sequence
por: Bornadiego, Ana, et al.
Publicado: (2021)

5-Bromo-1H-pyrrolo[2,3-b]pyridine
por: Štarha, Pavel, et al.
Publicado: (2013)

Raising the Diversity of Ugi Reactions Through Selective Alkylations and Allylations of Ugi Adducts
por: Zidan, Alaa, et al.
Publicado: (2019)

Diverse Isoquinoline Scaffolds by Ugi/Pomeranz–Fritsch and Ugi/Schlittler–Müller Reactions
por: Wang, Yuanze, et al.
Publicado: (2019)

Enantioselective Ugi and Ugi-azide reactions catalyzed by anionic stereogenic-at-cobalt(III) complexes
por: Sun, Bing-Bing, et al.
Publicado: (2022)

Access to pyrrolo-pyridines by gold-catalyzed hydroarylation of pyrroles tethered to terminal alkynes
por: Borsini, Elena, et al.
Publicado: (2011)

Synthesis of imidazo[1,2-a]pyridine-containing peptidomimetics by tandem of Groebke–Blackburn–Bienaymé and Ugi reactions
por: Kolomiiets, Oleksandr V, et al.
Publicado: (2023)

Synthesis of acylhydrazino-peptomers, a new class of peptidomimetics, by consecutive Ugi and hydrazino-Ugi reactions
por: Barreto, Angélica de Fátima S, et al.
Publicado: (2016)

Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles
por: Wang, Qian, et al.
Publicado: (2019)

A Conversation with Ting Zhu
por: Peplow, Mark
Publicado: (2018)

An intramolecular hydrogen bond-promoted “green” Ugi cascade reaction for the synthesis of 2,5-diketopiperazines with anticancer activity
por: Li, Jie, et al.
Publicado: (2022)

Synthesis of 2-Tetrazolylmethyl-isoindolin-1-ones via a One-Pot Ugi-Azide/(N-Acylation/exo-Diels–Alder)/Dehydration Process
por: Rentería-Gómez, Angel, et al.
Publicado: (2016)

Copper–phenanthroline catalysts for regioselective synthesis of pyrrolo[3′,4′:3,4]pyrrolo[1,2-a]furoquinolines/phenanthrolines and of pyrrolo[1,2-a]phenanthrolines under mild conditions
por: Paira, Rupankar, et al.
Publicado: (2014)

1-Methyl-7-(4-nitrophenyl)-3-phenylpyrazolo[3,4-b]pyrrolo[3,4-d]pyridine-6,8(3H,7H)-dione
por: Sabino, Jose R., et al.
Publicado: (2008)

Correction to Pd-Catalyzed de Novo Assembly of Diversely Substituted Indole-Fused Polyheterocycles
por: Wang, Qian, et al.
Publicado: (2020)

Synthesis of Diaminoacetic Acid Derivatives as a Promising Scaffold for the Synthesis of Polyheterocyclic Cage Compounds
por: Paromov, Artyom E., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_3luvo3tng71p96ksdvns2l8ubi