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Zeolites as Ingredients of Medicinal Products

Development of new medicinal products for particular therapeutic treatment or for better manipulations with better quality and less side effects are possible as a result of advanced inorganic and organic materials application, among which zeolites, due to their properties and versatility, have been...

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Autores principales: Souza, Iane M. S., García-Villén, Fátima, Viseras, César, Perger, Sibele B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221298/
https://www.ncbi.nlm.nih.gov/pubmed/37242594
http://dx.doi.org/10.3390/pharmaceutics15051352
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author Souza, Iane M. S.
García-Villén, Fátima
Viseras, César
Perger, Sibele B. C.
author_facet Souza, Iane M. S.
García-Villén, Fátima
Viseras, César
Perger, Sibele B. C.
author_sort Souza, Iane M. S.
collection PubMed
description Development of new medicinal products for particular therapeutic treatment or for better manipulations with better quality and less side effects are possible as a result of advanced inorganic and organic materials application, among which zeolites, due to their properties and versatility, have been gaining attention. This paper is an overview of the development in the use of zeolite materials and their composites and modifications as medicinal products for several purposes such as active agents, carriers, for topical treatments, oral formulations, anticancer, the composition of theragnostic systems, vaccines, parenteral dosage forms, tissue engineering, etc. The objective of this review is to explore the main properties of zeolites and associate them with their drug interaction, mainly addressing the advances and studies related to the use of zeolites for different types of treatments due to their zeolite characteristics such as molecule storage capacity, physical and chemical stability, cation exchange capacity, and possibility of functionalization. The use of computational tools to predict the drug—zeolite interaction is also explored. As conclusion was possible to realize the possibilities and versatility of zeolite applications as being able to act in several aspects of medicinal products.
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spelling pubmed-102212982023-05-28 Zeolites as Ingredients of Medicinal Products Souza, Iane M. S. García-Villén, Fátima Viseras, César Perger, Sibele B. C. Pharmaceutics Review Development of new medicinal products for particular therapeutic treatment or for better manipulations with better quality and less side effects are possible as a result of advanced inorganic and organic materials application, among which zeolites, due to their properties and versatility, have been gaining attention. This paper is an overview of the development in the use of zeolite materials and their composites and modifications as medicinal products for several purposes such as active agents, carriers, for topical treatments, oral formulations, anticancer, the composition of theragnostic systems, vaccines, parenteral dosage forms, tissue engineering, etc. The objective of this review is to explore the main properties of zeolites and associate them with their drug interaction, mainly addressing the advances and studies related to the use of zeolites for different types of treatments due to their zeolite characteristics such as molecule storage capacity, physical and chemical stability, cation exchange capacity, and possibility of functionalization. The use of computational tools to predict the drug—zeolite interaction is also explored. As conclusion was possible to realize the possibilities and versatility of zeolite applications as being able to act in several aspects of medicinal products. MDPI 2023-04-28 /pmc/articles/PMC10221298/ /pubmed/37242594 http://dx.doi.org/10.3390/pharmaceutics15051352 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Souza, Iane M. S.
García-Villén, Fátima
Viseras, César
Perger, Sibele B. C.
Zeolites as Ingredients of Medicinal Products
title Zeolites as Ingredients of Medicinal Products
title_full Zeolites as Ingredients of Medicinal Products
title_fullStr Zeolites as Ingredients of Medicinal Products
title_full_unstemmed Zeolites as Ingredients of Medicinal Products
title_short Zeolites as Ingredients of Medicinal Products
title_sort zeolites as ingredients of medicinal products
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221298/
https://www.ncbi.nlm.nih.gov/pubmed/37242594
http://dx.doi.org/10.3390/pharmaceutics15051352
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