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Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age

Introduction: Recent research has highlighted an increased incidence of ischemic stroke (IS) in young adults, along with a higher percentage of vascular risk factors at younger ages. This study aimed to estimate the in-hospital incidence of IS and associated comorbidities by sex and age group in Spa...

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Autores principales: Amaya Pascasio, Laura, Blanco Ruiz, Marina, Milán Pinilla, Rodrigo, García Torrecillas, Juan Manuel, Arjona Padillo, Antonio, Del Toro Pérez, Cristina, Martínez-Sánchez, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221310/
https://www.ncbi.nlm.nih.gov/pubmed/37240938
http://dx.doi.org/10.3390/jpm13050768
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author Amaya Pascasio, Laura
Blanco Ruiz, Marina
Milán Pinilla, Rodrigo
García Torrecillas, Juan Manuel
Arjona Padillo, Antonio
Del Toro Pérez, Cristina
Martínez-Sánchez, Patricia
author_facet Amaya Pascasio, Laura
Blanco Ruiz, Marina
Milán Pinilla, Rodrigo
García Torrecillas, Juan Manuel
Arjona Padillo, Antonio
Del Toro Pérez, Cristina
Martínez-Sánchez, Patricia
author_sort Amaya Pascasio, Laura
collection PubMed
description Introduction: Recent research has highlighted an increased incidence of ischemic stroke (IS) in young adults, along with a higher percentage of vascular risk factors at younger ages. This study aimed to estimate the in-hospital incidence of IS and associated comorbidities by sex and age group in Spain. Methods: A retrospective analysis of the Spain Nationwide Inpatient Sample database from 2016 to 2019 was conducted, which included adult patients with IS. In-hospital incidence and mortality rates were estimated, and a descriptive analysis of the main comorbidities was performed, stratified by sex and age groups. Results: A total of 186,487 patients were included, with a median age of 77 (IQR 66–85) years and 53.3% were male. Of these, 9162 (5%) were aged between 18 and 50 years. The estimated incidence of IS in adults younger than 50 years ranged from 11.9 to 13.5 per 100,000 inhabitants during the study period, with a higher incidence in men. The overall in-hospital mortality was 12.6%. Young adults with IS had a higher prevalence of most vascular risk factors compared to the general Spanish population, with a specific distribution according to sex and age. Conclusions: This study provides estimates of the incidence of IS and the prevalence of vascular risk factors and comorbidities associated with IS in Spain, stratified by sex and age, using a national registry of hospital admissions. These findings should be considered in terms of both primary and secondary prevention strategies.
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spelling pubmed-102213102023-05-28 Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age Amaya Pascasio, Laura Blanco Ruiz, Marina Milán Pinilla, Rodrigo García Torrecillas, Juan Manuel Arjona Padillo, Antonio Del Toro Pérez, Cristina Martínez-Sánchez, Patricia J Pers Med Article Introduction: Recent research has highlighted an increased incidence of ischemic stroke (IS) in young adults, along with a higher percentage of vascular risk factors at younger ages. This study aimed to estimate the in-hospital incidence of IS and associated comorbidities by sex and age group in Spain. Methods: A retrospective analysis of the Spain Nationwide Inpatient Sample database from 2016 to 2019 was conducted, which included adult patients with IS. In-hospital incidence and mortality rates were estimated, and a descriptive analysis of the main comorbidities was performed, stratified by sex and age groups. Results: A total of 186,487 patients were included, with a median age of 77 (IQR 66–85) years and 53.3% were male. Of these, 9162 (5%) were aged between 18 and 50 years. The estimated incidence of IS in adults younger than 50 years ranged from 11.9 to 13.5 per 100,000 inhabitants during the study period, with a higher incidence in men. The overall in-hospital mortality was 12.6%. Young adults with IS had a higher prevalence of most vascular risk factors compared to the general Spanish population, with a specific distribution according to sex and age. Conclusions: This study provides estimates of the incidence of IS and the prevalence of vascular risk factors and comorbidities associated with IS in Spain, stratified by sex and age, using a national registry of hospital admissions. These findings should be considered in terms of both primary and secondary prevention strategies. MDPI 2023-04-29 /pmc/articles/PMC10221310/ /pubmed/37240938 http://dx.doi.org/10.3390/jpm13050768 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Amaya Pascasio, Laura
Blanco Ruiz, Marina
Milán Pinilla, Rodrigo
García Torrecillas, Juan Manuel
Arjona Padillo, Antonio
Del Toro Pérez, Cristina
Martínez-Sánchez, Patricia
Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age
title Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age
title_full Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age
title_fullStr Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age
title_full_unstemmed Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age
title_short Stroke in Young Adults in Spain: Epidemiology and Risk Factors by Age
title_sort stroke in young adults in spain: epidemiology and risk factors by age
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221310/
https://www.ncbi.nlm.nih.gov/pubmed/37240938
http://dx.doi.org/10.3390/jpm13050768
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