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Differential Expression of ABC Transporter Genes in Brain Vessels vs. Peripheral Tissues and Vessels from Human, Mouse and Rat

Background: ATP-binding cassette (ABC) transporters comprise a superfamily of genes encoding membrane proteins with nucleotide-binding domains (NBD). These transporters, including drug efflux across the blood–brain barrier (BBB), carry a variety of substrates through plasma membranes against substra...

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Detalles Bibliográficos
Autores principales: Zhang, Wandong, Liu, Qing Yan, Haqqani, Arsalan S., Liu, Ziying, Sodja, Caroline, Leclerc, Sonia, Baumann, Ewa, Delaney, Christie E., Brunette, Eric, Stanimirovic, Danica B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221359/
https://www.ncbi.nlm.nih.gov/pubmed/37242805
http://dx.doi.org/10.3390/pharmaceutics15051563