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Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds

With the increasing need for effective compounds against cancer or pathogen-borne diseases, the development of new tools to investigate the enzymatic activity of biomarkers is necessary. Among these biomarkers are DNA topoisomerases, which are key enzymes that modify DNA and regulate DNA topology du...

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Detalles Bibliográficos
Autores principales: Keller, Josephine Geertsen, Petersen, Kamilla Vandsø, Mizielinski, Karol, Thiesen, Celine, Bjergbæk, Lotte, Reguera, Rosa M., Pérez-Pertejo, Yolanda, Balaña-Fouce, Rafael, Trejo, Angela, Masdeu, Carme, Alonso, Concepcion, Knudsen, Birgitta R., Tesauro, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221459/
https://www.ncbi.nlm.nih.gov/pubmed/37242440
http://dx.doi.org/10.3390/ph16050657