Modern Trends in Natural Antibiotic Discovery

Natural scaffolds remain an important basis for drug development. Therefore, approaches to natural bioactive compound discovery attract significant attention. In this account, we summarize modern and emerging trends in the screening and identification of natural antibiotics. The methods are divided...

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Detalles Bibliográficos
Autores principales: Baranova, Anna A., Alferova, Vera A., Korshun, Vladimir A., Tyurin, Anton P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221674/
https://www.ncbi.nlm.nih.gov/pubmed/37240718
http://dx.doi.org/10.3390/life13051073
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author Baranova, Anna A.
Alferova, Vera A.
Korshun, Vladimir A.
Tyurin, Anton P.
author_facet Baranova, Anna A.
Alferova, Vera A.
Korshun, Vladimir A.
Tyurin, Anton P.
author_sort Baranova, Anna A.
collection PubMed
description Natural scaffolds remain an important basis for drug development. Therefore, approaches to natural bioactive compound discovery attract significant attention. In this account, we summarize modern and emerging trends in the screening and identification of natural antibiotics. The methods are divided into three large groups: approaches based on microbiology, chemistry, and molecular biology. The scientific potential of the methods is illustrated with the most prominent and recent results.
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spelling pubmed-102216742023-05-28 Modern Trends in Natural Antibiotic Discovery Baranova, Anna A. Alferova, Vera A. Korshun, Vladimir A. Tyurin, Anton P. Life (Basel) Review Natural scaffolds remain an important basis for drug development. Therefore, approaches to natural bioactive compound discovery attract significant attention. In this account, we summarize modern and emerging trends in the screening and identification of natural antibiotics. The methods are divided into three large groups: approaches based on microbiology, chemistry, and molecular biology. The scientific potential of the methods is illustrated with the most prominent and recent results. MDPI 2023-04-23 /pmc/articles/PMC10221674/ /pubmed/37240718 http://dx.doi.org/10.3390/life13051073 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Baranova, Anna A.
Alferova, Vera A.
Korshun, Vladimir A.
Tyurin, Anton P.
Modern Trends in Natural Antibiotic Discovery
title Modern Trends in Natural Antibiotic Discovery
title_full Modern Trends in Natural Antibiotic Discovery
title_fullStr Modern Trends in Natural Antibiotic Discovery
title_full_unstemmed Modern Trends in Natural Antibiotic Discovery
title_short Modern Trends in Natural Antibiotic Discovery
title_sort modern trends in natural antibiotic discovery
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221674/
https://www.ncbi.nlm.nih.gov/pubmed/37240718
http://dx.doi.org/10.3390/life13051073
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