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Conformational antigenic heterogeneity as a cause of the persistent fraction in HIV-1 neutralization

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BACKGROUND: Neutralizing antibodies (NAbs) protect against HIV-1 acquisition in animal models and show promise in treatment of infection. They act by binding to the viral envelope glycoprotein (Env), thereby blocking its receptor interactions and fusogenic function. The potency of neutralization is...

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Detalles Bibliográficos
Autores principales:	Colin, Philippe, Ringe, Rajesh P., Yasmeen, Anila, Ozorowski, Gabriel, Ketas, Thomas J., Lee, Wen-Hsin, Ward, Andrew B., Moore, John P., Klasse, P. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221750/ https://www.ncbi.nlm.nih.gov/pubmed/37244989 http://dx.doi.org/10.1186/s12977-023-00624-9

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