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A γ-Glutamyl Transpeptidase (GGT)-Triggered Charge Reversal Drug-Delivery System for Cervical Cancer Treatment: In Vitro and In Vivo Investigation

Neutral/negatively charged nanoparticles are beneficial to reduce plasma protein adsorption and prolong their blood circulation time, while positively charged nanoparticles easily transverse the blood vessel endothelium into a tumor and easily penetrate the depth of the tumor via transcytosis. Γ-Glu...

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Detalles Bibliográficos
Autores principales: Fu, Jingxin, Lu, Likang, Li, Manzhen, Guo, Yaoyao, Han, Meihua, Guo, Yifei, Wang, Xiangtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221838/
https://www.ncbi.nlm.nih.gov/pubmed/37242579
http://dx.doi.org/10.3390/pharmaceutics15051335

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