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A γ-Glutamyl Transpeptidase (GGT)-Triggered Charge Reversal Drug-Delivery System for Cervical Cancer Treatment: In Vitro and In Vivo Investigation
Neutral/negatively charged nanoparticles are beneficial to reduce plasma protein adsorption and prolong their blood circulation time, while positively charged nanoparticles easily transverse the blood vessel endothelium into a tumor and easily penetrate the depth of the tumor via transcytosis. Γ-Glu...
Autores principales: | Fu, Jingxin, Lu, Likang, Li, Manzhen, Guo, Yaoyao, Han, Meihua, Guo, Yifei, Wang, Xiangtao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221838/ https://www.ncbi.nlm.nih.gov/pubmed/37242579 http://dx.doi.org/10.3390/pharmaceutics15051335 |
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