No Difference in the Prevalence of HIV-1 gag Cytotoxic T-Lymphocyte-Associated Escape Mutations in Viral Sequences from Early and Late Parts of the HIV-1 Subtype C Pandemic in Botswana

HIV is known to accumulate escape mutations in the gag gene in response to the immune response from cytotoxic T lymphocytes (CTLs). These mutations can occur within an individual as well as at a population level. The population of Botswana exhibits a high prevalence of HLA*B57 and HLA*B58, which are...

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Detalles Bibliográficos
Autores principales: Mokaleng, Baitshepi, Choga, Wonderful Tatenda, Bareng, Ontlametse Thato, Maruapula, Dorcas, Ditshwanelo, Doreen, Kelentse, Nametso, Mokgethi, Patrick, Moraka, Natasha Onalenna, Motswaledi, Modisa Sekhamo, Tawe, Leabaneng, Koofhethile, Catherine Kegakilwe, Moyo, Sikhulile, Zachariah, Matshediso, Gaseitsiwe, Simani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10221913/
https://www.ncbi.nlm.nih.gov/pubmed/37243104
http://dx.doi.org/10.3390/vaccines11051000

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