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Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group

(1) Background: Viral hepatitis C (HCV) and viral hepatitis B (HBV) are common co-infections in people living with HIV (PLWH). All PLWH should be vaccinated against HBV and hepatitis A (HAV) and treated for HBV and HCV. We aimed to compare testing, prophylaxis and treatment of viral hepatitis in PLW...

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Autores principales: Aimla, Kerstin, Kowalska, Justyna Dominika, Matulionyte, Raimonda, Mulabdic, Velida, Vassilenko, Anna, Bolokadze, Natalie, Jilich, David, Antoniak, Sergii, Oprea, Cristiana, Balayan, Tatevik, Harxhi, Arjan, Papadopoulos, Antonios, Lakatos, Botond, Vasylyev, Marta, Begovac, Josip, Yancheva, Nina, Streinu-Cercel, Anca, Verhaz, Antonija, Gokengin, Deniz, Dragovic, Gordana, Sojak, Lubomir, Skrzat-Klapaczyńska, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222000/
https://www.ncbi.nlm.nih.gov/pubmed/37243084
http://dx.doi.org/10.3390/vaccines11050980
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author Aimla, Kerstin
Kowalska, Justyna Dominika
Matulionyte, Raimonda
Mulabdic, Velida
Vassilenko, Anna
Bolokadze, Natalie
Jilich, David
Antoniak, Sergii
Oprea, Cristiana
Balayan, Tatevik
Harxhi, Arjan
Papadopoulos, Antonios
Lakatos, Botond
Vasylyev, Marta
Begovac, Josip
Yancheva, Nina
Streinu-Cercel, Anca
Verhaz, Antonija
Gokengin, Deniz
Dragovic, Gordana
Sojak, Lubomir
Skrzat-Klapaczyńska, Agata
author_facet Aimla, Kerstin
Kowalska, Justyna Dominika
Matulionyte, Raimonda
Mulabdic, Velida
Vassilenko, Anna
Bolokadze, Natalie
Jilich, David
Antoniak, Sergii
Oprea, Cristiana
Balayan, Tatevik
Harxhi, Arjan
Papadopoulos, Antonios
Lakatos, Botond
Vasylyev, Marta
Begovac, Josip
Yancheva, Nina
Streinu-Cercel, Anca
Verhaz, Antonija
Gokengin, Deniz
Dragovic, Gordana
Sojak, Lubomir
Skrzat-Klapaczyńska, Agata
author_sort Aimla, Kerstin
collection PubMed
description (1) Background: Viral hepatitis C (HCV) and viral hepatitis B (HBV) are common co-infections in people living with HIV (PLWH). All PLWH should be vaccinated against HBV and hepatitis A (HAV) and treated for HBV and HCV. We aimed to compare testing, prophylaxis and treatment of viral hepatitis in PLWH in Central and Eastern Europe (CEE) in 2019 and 2022. (2) Methods: Data was collected through two on-line surveys conducted in 2019 and 2022 among 18 countries of the Euroguidelines in CEE (ECEE) Network Group. (3) Results: In all 18 countries the standard of care was to screen all PLWH for HBV and HCV both years; screening of HAV was routine in 2019 in 54.5% and in 2022 47.4% of clinics. Vaccination of PLWH against HAV was available in 2019 in 16.7%, in 2022 in 22.2% countries. Vaccination against HBV was available routinely and free of charge in 50% of clinics both in 2019 and 2022. In HIV/HBV co-infected the choice of NRTI was tenofovir-based in 94.4% of countries in both years. All clinics that responded had access to direct-acting antivirals (DAAs) but 50% still had limitations for treatment. (4) Conclusions: Although testing for HBV and HCV was good, testing for HAV is insufficient. Vaccination against HBV and especially against HAV has room for improvement; furthermore, HCV treatment access needs to overcome restrictions.
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spelling pubmed-102220002023-05-28 Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group Aimla, Kerstin Kowalska, Justyna Dominika Matulionyte, Raimonda Mulabdic, Velida Vassilenko, Anna Bolokadze, Natalie Jilich, David Antoniak, Sergii Oprea, Cristiana Balayan, Tatevik Harxhi, Arjan Papadopoulos, Antonios Lakatos, Botond Vasylyev, Marta Begovac, Josip Yancheva, Nina Streinu-Cercel, Anca Verhaz, Antonija Gokengin, Deniz Dragovic, Gordana Sojak, Lubomir Skrzat-Klapaczyńska, Agata Vaccines (Basel) Brief Report (1) Background: Viral hepatitis C (HCV) and viral hepatitis B (HBV) are common co-infections in people living with HIV (PLWH). All PLWH should be vaccinated against HBV and hepatitis A (HAV) and treated for HBV and HCV. We aimed to compare testing, prophylaxis and treatment of viral hepatitis in PLWH in Central and Eastern Europe (CEE) in 2019 and 2022. (2) Methods: Data was collected through two on-line surveys conducted in 2019 and 2022 among 18 countries of the Euroguidelines in CEE (ECEE) Network Group. (3) Results: In all 18 countries the standard of care was to screen all PLWH for HBV and HCV both years; screening of HAV was routine in 2019 in 54.5% and in 2022 47.4% of clinics. Vaccination of PLWH against HAV was available in 2019 in 16.7%, in 2022 in 22.2% countries. Vaccination against HBV was available routinely and free of charge in 50% of clinics both in 2019 and 2022. In HIV/HBV co-infected the choice of NRTI was tenofovir-based in 94.4% of countries in both years. All clinics that responded had access to direct-acting antivirals (DAAs) but 50% still had limitations for treatment. (4) Conclusions: Although testing for HBV and HCV was good, testing for HAV is insufficient. Vaccination against HBV and especially against HAV has room for improvement; furthermore, HCV treatment access needs to overcome restrictions. MDPI 2023-05-14 /pmc/articles/PMC10222000/ /pubmed/37243084 http://dx.doi.org/10.3390/vaccines11050980 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Brief Report
Aimla, Kerstin
Kowalska, Justyna Dominika
Matulionyte, Raimonda
Mulabdic, Velida
Vassilenko, Anna
Bolokadze, Natalie
Jilich, David
Antoniak, Sergii
Oprea, Cristiana
Balayan, Tatevik
Harxhi, Arjan
Papadopoulos, Antonios
Lakatos, Botond
Vasylyev, Marta
Begovac, Josip
Yancheva, Nina
Streinu-Cercel, Anca
Verhaz, Antonija
Gokengin, Deniz
Dragovic, Gordana
Sojak, Lubomir
Skrzat-Klapaczyńska, Agata
Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group
title Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group
title_full Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group
title_fullStr Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group
title_full_unstemmed Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group
title_short Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV—Data from ECEE Network Group
title_sort vaccination against hbv and hav as mode of hepatitis prevention among people living with hiv—data from ecee network group
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222000/
https://www.ncbi.nlm.nih.gov/pubmed/37243084
http://dx.doi.org/10.3390/vaccines11050980
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