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Model-Based Analysis of In Vivo Release Data of Levonorgestrel Implants: Projecting Long-Term Systemic Exposure
Levonorgestrel (LNG) is a progestin used in many contraceptive formulations, including subcutaneous implants. There is an unmet need for developing long-acting formulations for LNG. To develop long-acting formulations, release functions need to be investigated for LNG implant. Therefore, a release m...
Autores principales: | Kim, Soyoung, Cicali, Brian, Pressly, Michelle, Da Silva, Lais, Wendl, Thomas, Vozmediano, Valvanera, Schmidt, Stephan, Cristofoletti, Rodrigo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222093/ https://www.ncbi.nlm.nih.gov/pubmed/37242635 http://dx.doi.org/10.3390/pharmaceutics15051393 |
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