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Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review
Background: Cerebral venous sinus thrombosis (CVST) is a rare manifestation of thrombosis commonly caused by thrombophilia, hormonal-related factors, non-cerebral malignancy, and hematologic diseases. The aim of this review was to identify and summarize rare CVST cases. Methods: A literature search...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222108/ https://www.ncbi.nlm.nih.gov/pubmed/37240823 http://dx.doi.org/10.3390/life13051178 |
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author | Theologou, Rafaella Nteveros, Antonios Artemiadis, Artemios Faropoulos, Konstantinos |
author_facet | Theologou, Rafaella Nteveros, Antonios Artemiadis, Artemios Faropoulos, Konstantinos |
author_sort | Theologou, Rafaella |
collection | PubMed |
description | Background: Cerebral venous sinus thrombosis (CVST) is a rare manifestation of thrombosis commonly caused by thrombophilia, hormonal-related factors, non-cerebral malignancy, and hematologic diseases. The aim of this review was to identify and summarize rare CVST cases. Methods: A literature search of the Medline database was performed in November 2022. CVST cases of a common cause were excluded. Demographic and clinical data were extracted. Eligible cases were categorized into inflammatory, primary CNS tumors, post-operative/traumatic, and idiopathic groups to allow statistical group comparisons. Results: 76 cases were analyzed. Idiopathic CVST was most frequently reported followed by inflammatory, post-traumatic/operative and primary CNS tumor causes. The intracranial hemorrhage rate was 23.7% and it was found to increase in the inflammatory group (45.8%). Anticoagulation was used in the majority of cases and it was significantly related to better outcomes. A low rate of anticoagulation use (43.8%) was found among CVST cases in the post-operative/traumatic group. The overall mortality rate was 9.8%. 82.4% of patients showed significant early improvement. Conclusions: Most rare CVST cases were either of idiopathic or inflammatory origin. Interestingly, hemorrhage occurred often he idiopathic CVST cases. A low rate of anticoagulation use in neurosurgical CVST cases after trauma or head surgery was observed. |
format | Online Article Text |
id | pubmed-10222108 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102221082023-05-28 Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review Theologou, Rafaella Nteveros, Antonios Artemiadis, Artemios Faropoulos, Konstantinos Life (Basel) Systematic Review Background: Cerebral venous sinus thrombosis (CVST) is a rare manifestation of thrombosis commonly caused by thrombophilia, hormonal-related factors, non-cerebral malignancy, and hematologic diseases. The aim of this review was to identify and summarize rare CVST cases. Methods: A literature search of the Medline database was performed in November 2022. CVST cases of a common cause were excluded. Demographic and clinical data were extracted. Eligible cases were categorized into inflammatory, primary CNS tumors, post-operative/traumatic, and idiopathic groups to allow statistical group comparisons. Results: 76 cases were analyzed. Idiopathic CVST was most frequently reported followed by inflammatory, post-traumatic/operative and primary CNS tumor causes. The intracranial hemorrhage rate was 23.7% and it was found to increase in the inflammatory group (45.8%). Anticoagulation was used in the majority of cases and it was significantly related to better outcomes. A low rate of anticoagulation use (43.8%) was found among CVST cases in the post-operative/traumatic group. The overall mortality rate was 9.8%. 82.4% of patients showed significant early improvement. Conclusions: Most rare CVST cases were either of idiopathic or inflammatory origin. Interestingly, hemorrhage occurred often he idiopathic CVST cases. A low rate of anticoagulation use in neurosurgical CVST cases after trauma or head surgery was observed. MDPI 2023-05-12 /pmc/articles/PMC10222108/ /pubmed/37240823 http://dx.doi.org/10.3390/life13051178 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Systematic Review Theologou, Rafaella Nteveros, Antonios Artemiadis, Artemios Faropoulos, Konstantinos Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review |
title | Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review |
title_full | Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review |
title_fullStr | Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review |
title_full_unstemmed | Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review |
title_short | Rare Causes of Cerebral Venus Sinus Thrombosis: A Systematic Review |
title_sort | rare causes of cerebral venus sinus thrombosis: a systematic review |
topic | Systematic Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222108/ https://www.ncbi.nlm.nih.gov/pubmed/37240823 http://dx.doi.org/10.3390/life13051178 |
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