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Tracers for Cardiac Imaging: Targeting the Future of Viable Myocardium

Ischemic heart disease is the leading cause of mortality worldwide. In this context, myocardial viability is defined as the amount of myocardium that, despite contractile dysfunction, maintains metabolic and electrical function, having the potential for functional enhancement upon revascularization....

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Detalles Bibliográficos
Autores principales: Nappi, Carmela, Panico, Mariarosaria, Falzarano, Maria, Vallone, Carlo, Ponsiglione, Andrea, Cutillo, Paolo, Zampella, Emilia, Petretta, Mario, Cuocolo, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222155/
https://www.ncbi.nlm.nih.gov/pubmed/37242772
http://dx.doi.org/10.3390/pharmaceutics15051532
Descripción
Sumario:Ischemic heart disease is the leading cause of mortality worldwide. In this context, myocardial viability is defined as the amount of myocardium that, despite contractile dysfunction, maintains metabolic and electrical function, having the potential for functional enhancement upon revascularization. Recent advances have improved methods to detect myocardial viability. The current paper summarizes the pathophysiological basis of the current methods used to detect myocardial viability in light of the advancements in the development of new radiotracers for cardiac imaging.