Cargando…

Leocarpinolide B Attenuates Collagen Type II-Induced Arthritis by Inhibiting DNA Binding Activity of NF-κB

Rheumatoid arthritis (RA) is a chronic autoimmune disease triggered by a cascading inflammatory response. Sigesbeckia Herba (SH) has long been utilized as a traditional remedy to alleviate symptoms associated with rheumatism. Our previous study found that leocarpinolide B (LB), a sesquiterpene lacto...

Descripción completa

Detalles Bibliográficos
Autores principales:	Linghu, Ke-Gang, Zhao, Guan-Ding, Zhang, Dai-Yan, Xiong, Shi-Hang, Wu, Guo-Ping, Shen, Li-Yu, Cui, Wen-Qing, Zhang, Tian, Hu, Yuan-Jia, Guo, Bing, Shen, Xiang-Chun, Yu, Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222175/ https://www.ncbi.nlm.nih.gov/pubmed/37241980 http://dx.doi.org/10.3390/molecules28104241

Ejemplares similares

Sigesbeckia glabrescens Makino extract attenuated the collagen-induced arthritis through inhibiting the synovial hyperplasia and inflammation
por: Ma, Qiu Shuo, et al.
Publicado: (2020)

Novel Compound Q-1 Alleviates Type II Collagen-Induced Arthritis in Rats through the NF-κB Pathway
por: Xu, Ting, et al.
Publicado: (2021)

Sigesbeckia orientalis L. Extract Alleviated the Collagen Type II–Induced Arthritis Through Inhibiting Multi-Target–Mediated Synovial Hyperplasia and Inflammation
por: Linghu, Ke-Gang, et al.
Publicado: (2020)

1,8-Cineole Ameliorates LPS-Induced Vascular Endothelium Dysfunction in Mice via PPAR-γ Dependent Regulation of NF-κB
por: Linghu, Ke-Gang, et al.
Publicado: (2019)

Kinsenoside screening with a microfluidic chip attenuates gouty arthritis through inactivating NF-κB signaling in macrophages and protecting endothelial cells
por: Han, Qiao, et al.
Publicado: (2016)

Magnoflorine Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response via the NF-κB/MAPK Signaling Pathways
por: Wang, Lei, et al.
Publicado: (2023)

Guizhi-Shaoyao-Zhimu decoction attenuates bone erosion in rats that have collagen-induced arthritis via modulating NF‐κB signalling to suppress osteoclastogenesis
por: Wei, Shu-jun, et al.
Publicado: (2021)

Melittin acupoint injection in attenuating bone erosion in collagen-induced arthritis mice via inhibition of the RANKL/NF-κB signaling pathway
por: Liu, Fenfang, et al.
Publicado: (2023)

Anhuienoside C Ameliorates Collagen-Induced Arthritis through Inhibition of MAPK and NF-κB Signaling Pathways
por: Liu, Qing, et al.
Publicado: (2017)

Pharmacological Effect of Caulophyllum robustum on Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-κB, and Proinflammatory Cytokines In Vivo and In Vitro
por: Wang, Qiu-hong, et al.
Publicado: (2017)

CD38 Deficiency Downregulates the Onset and Pathogenesis of Collagen-Induced Arthritis through the NF-κB Pathway
por: Du, Yuna, et al.
Publicado: (2019)

Exenatide inhibits NF-κB and attenuates ER stress in diabetic cardiomyocyte models
por: Fu, Zhenhong, et al.
Publicado: (2020)

Alprostadil attenuates LPS-induced cardiomyocyte injury by inhibiting the Wnt5a/JNK/NF-κB pathway
por: Yu, T., et al.
Publicado: (2019)

Amelioration of collagen-induced arthritis using antigen-loaded dendritic cells modified with NF-κB decoy oligodeoxynucleotides
por: Jiang, Hongmei, et al.
Publicado: (2017)

TRAF6 neddylation drives inflammatory arthritis by increasing NF-κB activation
por: Liu, Kewei, et al.
Publicado: (2019)

Oridonin Prolongs the Survival of Mouse Cardiac Allografts by Attenuating the NF-κB/NLRP3 Pathway
por: Du, Xiaoxiao, et al.
Publicado: (2021)

TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling
por: Yang, Wanlei, et al.
Publicado: (2021)

(+)-JQ1 attenuated LPS-induced microglial inflammation via MAPK/NFκB signaling
por: Wang, Huanhuan, et al.
Publicado: (2018)

Cathepsin B Regulates Collagen Expression by Fibroblasts via Prolonging TLR2/NF-κB Activation
por: Li, Xue, et al.
Publicado: (2016)

Polyphyllin I Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response in Macrophages Through the NF-κB Pathway
por: Wang, Qiong, et al.
Publicado: (2018)

Hepatic NF‐κB‐Inducing Kinase and Inhibitor of NF‐κB Kinase Subunit α Promote Liver Oxidative Stress, Ferroptosis, and Liver Injury
por: Zhong, Xiao, et al.
Publicado: (2021)

AMPK attenuates SHH subgroup medulloblastoma growth and metastasis by inhibiting NF-κB activation
por: Cai, Jing, et al.
Publicado: (2023)

NFκB and Kidney Injury
por: Song, Ning, et al.
Publicado: (2019)

Suramin attenuates intervertebral disc degeneration by inhibiting NF-κB signalling pathway
por: Liu, Zi-Miao, et al.
Publicado: (2021)

SUMOylation of Dorsal attenuates Toll/NF-κB signaling
por: Hegde, Sushmitha, et al.
Publicado: (2022)

Deguelin Attenuates Allergic Airway Inflammation via Inhibition of NF-κb Pathway in Mice
por: Bao, Zhang, et al.
Publicado: (2017)

Disruption of NF-κB signaling by fluoxetine attenuates MGMT expression in glioma cells
por: Song, Tao, et al.
Publicado: (2015)

Shuangtengbitong tincture treatment of collagen-induced arthritis via downregulation of the expression of IL-6, IL-8, TNF-α and NF-κB
por: CHU, KEDAN, et al.
Publicado: (2013)

N-Acetyldopamine Dimer Attenuates DSS-Induced Ulcerative Colitis by Suppressing NF-κB and MAPK Pathways
por: Huang, Li-Jun, et al.
Publicado: (2022)

Inhibition of CCR8 attenuates Ang Ⅱ-induced vascular smooth muscle cell injury by suppressing the MAPK/NF-κB pathway
por: Liao, Lisi, et al.
Publicado: (2022)

Attenuation of Innate Immunity by Andrographolide Derivatives Through NF-κB Signaling Pathway
por: Nie, Xin, et al.
Publicado: (2017)

AMPK Inhibition Blocks ROS-NFκB Signaling and Attenuates Endotoxemia-Induced Liver Injury
por: Guo, Yuan, et al.
Publicado: (2014)

Nuclear Factor kappa B (NF-κB) Targeted Self-Assembled Nanoparticles Loaded with Methotrexate for Treatment of Rheumatoid Arthritis
por: Li, Xiong, et al.
Publicado: (2019)

REGγ promotes mantle cell lymphoma cell apoptosis by downregulating NF-κB signaling
por: Zeng, Xin-Xin, et al.
Publicado: (2023)

TXNIP/TRX/NF-κB and MAPK/NF-κB pathways involved in the cardiotoxicity induced by Venenum Bufonis in rats
por: Bi, Qi-rui, et al.
Publicado: (2016)

Triptolide attenuates proteinuria and podocyte apoptosis via inhibition of NF-κB/GADD45B
por: Wang, Ling, et al.
Publicado: (2018)

Salvianolic Acid B Suppresses Inflammatory Mediator Levels by Downregulating NF-κB in a Rat Model of Rheumatoid Arthritis
por: Xia, Zeng-Bing, et al.
Publicado: (2018)

Alpha‐lipoic acid downregulates TRPV1 receptor via NF‐κB and attenuates neuropathic pain in rats with diabetes
por: Zhang, Bing‐Yu, et al.
Publicado: (2020)

GBE50 Attenuates Inflammatory Response by Inhibiting the p38 MAPK and NF-κB Pathways in LPS-Stimulated Microglial Cells
por: He, Gai-ying, et al.
Publicado: (2014)

PARP-1 Inhibitor, DPQ, Attenuates LPS-Induced Acute Lung Injury through Inhibiting NF-κB-Mediated Inflammatory Response
por: Wang, Gang, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_hv76l9q1c50v30ibhtj2o8p4p7