Cargando…

Synthesis and Antiproliferative Insights of Lipophilic Ru(II)-Hydroxy Stearic Acid Hybrid Species

Metallodrugs represent a combination of multifunctionalities that are present concomitantly and can act differently on diverse biotargets. Their efficacy is often related to the lipophilic features exhibited both by long carbo-chains and the phosphine ligands. Three Ru(II) complexes containing hydro...

Descripción completa

Detalles Bibliográficos
Autores principales:	Drius, Giacomo, Bordoni, Silvia, Boga, Carla, Monari, Magda, Fiori, Jessica, Esposito, Erika, Zalambani, Chiara, Pincigher, Luca, Farruggia, Giovanna, Calonghi, Natalia, Micheletti, Gabriele
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222286/ https://www.ncbi.nlm.nih.gov/pubmed/37241793 http://dx.doi.org/10.3390/molecules28104051

Ejemplares similares

Effects of Regioisomerism on the Antiproliferative Activity of Hydroxystearic Acids on Human Cancer Cell Lines
por: Calonghi, Natalia, et al.
Publicado: (2022)

Ru-Controlled Thymine Tautomerization Frozen by a k(1)(O)-, k(2)(N,O)-Metallacycle: An Experimental and Theoretical Approach
por: Bordoni, Silvia, et al.
Publicado: (2023)

Synthesis of thia-Michael-Type Adducts between Naphthoquinones and N-Acetyl-L-Cysteine and Their Biological Activity
por: Micheletti, Gabriele, et al.
Publicado: (2022)

Myrcene: A Natural Compound Showing Anticancer Activity in HeLa Cells
por: Pincigher, Luca, et al.
Publicado: (2023)

Synthesis of 9-Hydroxystearic Acid Derivatives and Their Antiproliferative Activity on HT 29 Cancer Cells
por: Calonghi, Natalia, et al.
Publicado: (2019)

Synthesis of Novel Structural Hybrids between Aza-Heterocycles and Azelaic Acid Moiety with a Specific Activity on Osteosarcoma Cells
por: Micheletti, Gabriele, et al.
Publicado: (2020)

Synthesis and Antiproliferative Activity against Cancer Cells of Indole-Aryl-Amide Derivatives
por: Zhao, Junwei, et al.
Publicado: (2022)

Regioselectivity in Reactions between Bis(2-benzothiazolyl)ketone and Vinyl Grignard Reagents: C- versus O-alkylation—Part III †
por: Boga, Carla, et al.
Publicado: (2018)

Root Extracts of Two Cultivars of Paeonia Species: Lipid Composition and Biological Effects on Different Cell Lines: Preliminary Results
por: Calonghi, Natalia, et al.
Publicado: (2021)

Catalytic Hydrothermal Deoxygenation of Stearic Acid with Ru/C: Effects of Alcohol- and Carboxylic Acid-Based Hydrogen Donors
por: Wang, Jianyu, et al.
Publicado: (2023)

Stearic acid and carcinogenesis.
por: Habib, N. A., et al.
Publicado: (1987)

Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts
por: Ramos, Patrícia A. B., et al.
Publicado: (2016)

Indole Derivative Interacts with Estrogen Receptor Beta and Inhibits Human Ovarian Cancer Cell Growth
por: Verardi, Laura, et al.
Publicado: (2020)

Enhanced cellular uptake and photochemotherapeutic potential of a lipophilic strained Ru(ii) polypyridyl complex
por: Mehanna, Stephanie, et al.
Publicado: (2019)

Molecular Dynamics: Investigating the Self-Association of Stearic Acid and Heteroassociation of Stearic Acid–Water in Cyclohexane
por: Sharifi, Najib
Publicado: (2023)

C-C Coupling Reactions between Benzofurazan Derivatives and 1,3-Diaminobenzenes
por: Micheletti, Gabriele, et al.
Publicado: (2017)

Antiproliferative Activity of β-Hydroxy-β-Arylalkanoic Acids
por: Dilber, Sanda P., et al.
Publicado: (2007)

Role of D(−)-Lactic Acid in Prevention of Chlamydia trachomatis Infection in an In Vitro Model of HeLa Cells
por: Zalambani, Chiara, et al.
Publicado: (2023)

Evaluation of the Antiproliferative Properties of CpRu Complexes Containing N-Methylated Triazaphosphaadamantane Derivatives
por: Alguacil, Andres, et al.
Publicado: (2023)

Highly conjugated architectures and labile reaction intermediates from coupling between 10π electron-deficient heteroaromatics and sym-trihydroxy- or triamino-benzene derivatives
por: Micheletti, Gabriele, et al.
Publicado: (2018)

Chemical Profile of Lipophilic Fractions of Different Parts of Zizyphus lotus L. by GC-MS and Evaluation of Their Antiproliferative and Antibacterial Activities
por: Zazouli, Sofia, et al.
Publicado: (2022)

Dietary stearic acid regulates mitochondria in vivo in humans
por: Senyilmaz-Tiebe, Deniz, et al.
Publicado: (2018)

Nanomicellar Lenalidomide–Fenretinide Combination Suppresses Tumor Growth in an MYCN Amplified Neuroblastoma Tumor
por: Orienti, Isabella, et al.
Publicado: (2020)

A Novel Nanomicellar Combination of Fenretinide and Lenalidomide Shows Marked Antitumor Activity in a Neuroblastoma Xenograft Model
por: Orienti, Isabella, et al.
Publicado: (2019)

Computational Identification of Stearic Acid as a Potential PDK1 Inhibitor and In Vitro Validation of Stearic Acid as Colon Cancer Therapeutic in Combination with 5-Fluorouracil
por: Mitchel, Jonathan, et al.
Publicado: (2021)

Natural Astaxanthin Is a Green Antioxidant Able to Counteract Lipid Peroxidation and Ferroptotic Cell Death
por: Rizzardi, Nicola, et al.
Publicado: (2022)

Amidinoquinoxaline-Based Nitrones as Lipophilic Antioxidants
por: Gruber, Nadia, et al.
Publicado: (2021)

Stearic acid content of abdominal adipose tissues in obese women
por: Caron-Jobin, M, et al.
Publicado: (2012)

Improvement of Liver Cell Therapy in Rats by Dietary Stearic Acid
por: Goradel, Nasser Hashemi, et al.
Publicado: (2016)

Antiproliferative effect of mifepristone (RU486) on human neuroblastoma cells (SK-N-SH): in vitro and in vivo studies
por: Casulari, L.A., et al.
Publicado: (2020)

Synthesis and investigation of antiproliferative activity of Ru-NHC complexes against C6 and HeLa cancer cells
por: PAŞAHAN, Ramazan, et al.
Publicado: (2022)

Intriguing enigma of nitrobenzofuroxan's ‘Sphinx’: Boulton–Katritzky rearrangement or unusual evidence of the N-1/N-3-oxide rearrangement?
por: Micheletti, Gabriele, et al.
Publicado: (2020)

Ruminal microbe of biohydrogenation of trans-vaccenic acid to stearic acid in vitro
por: Li, Dan, et al.
Publicado: (2012)

Correction: Preparation of glycerol monostearate from glycerol carbonate and stearic acid
por: Han, Li, et al.
Publicado: (2018)

Triazene salts: Design, synthesis, ctDNA interaction, lipophilicity determination, DFT calculation, and antiproliferative activity against human cancer cell lines
por: Cytarska, Joanna, et al.
Publicado: (2019)

Synthesis of Novel Tryptamine Derivatives and Their Biological Activity as Antitumor Agents
por: Simonetti, Giorgia, et al.
Publicado: (2021)

Chemosensitization by lipophilic nitroimidazoles.
por: Twentyman, P. R., et al.
Publicado: (1983)

Hydrophilic or Lipophilic Statins?
por: Climent, Elisenda, et al.
Publicado: (2021)

A novel palmitic acid hydroxy stearic acid (5‐PAHSA) plays a neuroprotective role by inhibiting phosphorylation of the m‐TOR‐ULK1 pathway and regulating autophagy
por: Wang, Jian‐tao, et al.
Publicado: (2021)

Unusual enantioselective cytoplasm-to-nucleus translocation and photosensitization of the chiral Ru(II) cationic complex via simple ion-pairing with lipophilic weak acid counter-anions
por: Chao, Xi-Juan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_q6grtgq1tg06bperebmeolvp9t