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Current Treatment Approaches for Thymic Epithelial Tumors
Thymic epithelial tumors (TETs), including thymoma, thymic carcinoma and neuroendocrine tumors, are uncommon tumors that originate from the epithelial cells of the thymus. Nevertheless, despite their rarity, they represent the most common tumor type located in the anterior mediastinum. Therapeutic c...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222654/ https://www.ncbi.nlm.nih.gov/pubmed/37240815 http://dx.doi.org/10.3390/life13051170 |
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author | Tartarone, Alfredo Lerose, Rosa Lettini, Alessandro Rocco Tartarone, Marina |
author_facet | Tartarone, Alfredo Lerose, Rosa Lettini, Alessandro Rocco Tartarone, Marina |
author_sort | Tartarone, Alfredo |
collection | PubMed |
description | Thymic epithelial tumors (TETs), including thymoma, thymic carcinoma and neuroendocrine tumors, are uncommon tumors that originate from the epithelial cells of the thymus. Nevertheless, despite their rarity, they represent the most common tumor type located in the anterior mediastinum. Therapeutic choices based on staging and histology may include surgery with or without neoadjuvant or adjuvant therapy represented by chemotherapy, radiotherapy or chemo-radiotherapy. For patients with advanced or metastatic TETs, platinum-based chemotherapy remains the standard first-line treatment; however, some new drugs and combinations are currently under evaluation. In any case, proper management of patients with TETs requires a multidisciplinary team approach to personalize care for each patient. |
format | Online Article Text |
id | pubmed-10222654 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102226542023-05-28 Current Treatment Approaches for Thymic Epithelial Tumors Tartarone, Alfredo Lerose, Rosa Lettini, Alessandro Rocco Tartarone, Marina Life (Basel) Review Thymic epithelial tumors (TETs), including thymoma, thymic carcinoma and neuroendocrine tumors, are uncommon tumors that originate from the epithelial cells of the thymus. Nevertheless, despite their rarity, they represent the most common tumor type located in the anterior mediastinum. Therapeutic choices based on staging and histology may include surgery with or without neoadjuvant or adjuvant therapy represented by chemotherapy, radiotherapy or chemo-radiotherapy. For patients with advanced or metastatic TETs, platinum-based chemotherapy remains the standard first-line treatment; however, some new drugs and combinations are currently under evaluation. In any case, proper management of patients with TETs requires a multidisciplinary team approach to personalize care for each patient. MDPI 2023-05-12 /pmc/articles/PMC10222654/ /pubmed/37240815 http://dx.doi.org/10.3390/life13051170 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Tartarone, Alfredo Lerose, Rosa Lettini, Alessandro Rocco Tartarone, Marina Current Treatment Approaches for Thymic Epithelial Tumors |
title | Current Treatment Approaches for Thymic Epithelial Tumors |
title_full | Current Treatment Approaches for Thymic Epithelial Tumors |
title_fullStr | Current Treatment Approaches for Thymic Epithelial Tumors |
title_full_unstemmed | Current Treatment Approaches for Thymic Epithelial Tumors |
title_short | Current Treatment Approaches for Thymic Epithelial Tumors |
title_sort | current treatment approaches for thymic epithelial tumors |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222654/ https://www.ncbi.nlm.nih.gov/pubmed/37240815 http://dx.doi.org/10.3390/life13051170 |
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