Cargando…
Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin
Eclipta prostrata (E. prostrata) has several biological activities, including antibacterial and anti-inflammatory activities, that improve wound healing. It is well known that physical properties and pH environment are crucial considerations when developing wound dressings containing medicinal plant...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222729/ https://www.ncbi.nlm.nih.gov/pubmed/37242467 http://dx.doi.org/10.3390/ph16050685 |
_version_ | 1785049769246195712 |
---|---|
author | Hasatsri, Sukhontha Suthi, Jariya Siriwut, Nattaporn Charoensappakit, Onjira |
author_facet | Hasatsri, Sukhontha Suthi, Jariya Siriwut, Nattaporn Charoensappakit, Onjira |
author_sort | Hasatsri, Sukhontha |
collection | PubMed |
description | Eclipta prostrata (E. prostrata) has several biological activities, including antibacterial and anti-inflammatory activities, that improve wound healing. It is well known that physical properties and pH environment are crucial considerations when developing wound dressings containing medicinal plant extracts in order to create an appropriate environment for wound healing. In this study, we prepared a foam dressing containing E. prostrata leaf extract and gelatin. Chemical composition was verified using Fourier-transform infrared spectroscopy (FTIR) and pore structure was obtained using scanning electron microscopy (SEM). The physical properties of the dressing, including absorption and dehydration properties, were also evaluated. The chemical properties were measured to determine the pH environment after the dressing was suspended in water. The results revealed that the E. prostrata dressings had a pore structure with an appropriate pore size (313.25 ± 76.51 µm and 383.26 ± 64.45 µm for the E. prostrata A and E. prostrata B dressings, respectively). The E. prostrata B dressings showed a higher percentage of weight increase in the first hour and a faster dehydration rate in the first 4 h. Furthermore, the E. prostrata dressings had a slightly acidic environment (5.28 ± 0.02 and 5.38 ± 0.02 for the E. prostrata A and E. prostrata B dressings at 48 h, respectively). |
format | Online Article Text |
id | pubmed-10222729 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102227292023-05-28 Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin Hasatsri, Sukhontha Suthi, Jariya Siriwut, Nattaporn Charoensappakit, Onjira Pharmaceuticals (Basel) Article Eclipta prostrata (E. prostrata) has several biological activities, including antibacterial and anti-inflammatory activities, that improve wound healing. It is well known that physical properties and pH environment are crucial considerations when developing wound dressings containing medicinal plant extracts in order to create an appropriate environment for wound healing. In this study, we prepared a foam dressing containing E. prostrata leaf extract and gelatin. Chemical composition was verified using Fourier-transform infrared spectroscopy (FTIR) and pore structure was obtained using scanning electron microscopy (SEM). The physical properties of the dressing, including absorption and dehydration properties, were also evaluated. The chemical properties were measured to determine the pH environment after the dressing was suspended in water. The results revealed that the E. prostrata dressings had a pore structure with an appropriate pore size (313.25 ± 76.51 µm and 383.26 ± 64.45 µm for the E. prostrata A and E. prostrata B dressings, respectively). The E. prostrata B dressings showed a higher percentage of weight increase in the first hour and a faster dehydration rate in the first 4 h. Furthermore, the E. prostrata dressings had a slightly acidic environment (5.28 ± 0.02 and 5.38 ± 0.02 for the E. prostrata A and E. prostrata B dressings at 48 h, respectively). MDPI 2023-05-02 /pmc/articles/PMC10222729/ /pubmed/37242467 http://dx.doi.org/10.3390/ph16050685 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Hasatsri, Sukhontha Suthi, Jariya Siriwut, Nattaporn Charoensappakit, Onjira Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin |
title | Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin |
title_full | Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin |
title_fullStr | Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin |
title_full_unstemmed | Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin |
title_short | Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin |
title_sort | physical properties and ph environment of foam dressing containing eclipta prostrata leaf extract and gelatin |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222729/ https://www.ncbi.nlm.nih.gov/pubmed/37242467 http://dx.doi.org/10.3390/ph16050685 |
work_keys_str_mv | AT hasatsrisukhontha physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin AT suthijariya physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin AT siriwutnattaporn physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin AT charoensappakitonjira physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin |