Cargando…

Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin

Eclipta prostrata (E. prostrata) has several biological activities, including antibacterial and anti-inflammatory activities, that improve wound healing. It is well known that physical properties and pH environment are crucial considerations when developing wound dressings containing medicinal plant...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasatsri, Sukhontha, Suthi, Jariya, Siriwut, Nattaporn, Charoensappakit, Onjira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222729/
https://www.ncbi.nlm.nih.gov/pubmed/37242467
http://dx.doi.org/10.3390/ph16050685
_version_ 1785049769246195712
author Hasatsri, Sukhontha
Suthi, Jariya
Siriwut, Nattaporn
Charoensappakit, Onjira
author_facet Hasatsri, Sukhontha
Suthi, Jariya
Siriwut, Nattaporn
Charoensappakit, Onjira
author_sort Hasatsri, Sukhontha
collection PubMed
description Eclipta prostrata (E. prostrata) has several biological activities, including antibacterial and anti-inflammatory activities, that improve wound healing. It is well known that physical properties and pH environment are crucial considerations when developing wound dressings containing medicinal plant extracts in order to create an appropriate environment for wound healing. In this study, we prepared a foam dressing containing E. prostrata leaf extract and gelatin. Chemical composition was verified using Fourier-transform infrared spectroscopy (FTIR) and pore structure was obtained using scanning electron microscopy (SEM). The physical properties of the dressing, including absorption and dehydration properties, were also evaluated. The chemical properties were measured to determine the pH environment after the dressing was suspended in water. The results revealed that the E. prostrata dressings had a pore structure with an appropriate pore size (313.25 ± 76.51 µm and 383.26 ± 64.45 µm for the E. prostrata A and E. prostrata B dressings, respectively). The E. prostrata B dressings showed a higher percentage of weight increase in the first hour and a faster dehydration rate in the first 4 h. Furthermore, the E. prostrata dressings had a slightly acidic environment (5.28 ± 0.02 and 5.38 ± 0.02 for the E. prostrata A and E. prostrata B dressings at 48 h, respectively).
format Online
Article
Text
id pubmed-10222729
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-102227292023-05-28 Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin Hasatsri, Sukhontha Suthi, Jariya Siriwut, Nattaporn Charoensappakit, Onjira Pharmaceuticals (Basel) Article Eclipta prostrata (E. prostrata) has several biological activities, including antibacterial and anti-inflammatory activities, that improve wound healing. It is well known that physical properties and pH environment are crucial considerations when developing wound dressings containing medicinal plant extracts in order to create an appropriate environment for wound healing. In this study, we prepared a foam dressing containing E. prostrata leaf extract and gelatin. Chemical composition was verified using Fourier-transform infrared spectroscopy (FTIR) and pore structure was obtained using scanning electron microscopy (SEM). The physical properties of the dressing, including absorption and dehydration properties, were also evaluated. The chemical properties were measured to determine the pH environment after the dressing was suspended in water. The results revealed that the E. prostrata dressings had a pore structure with an appropriate pore size (313.25 ± 76.51 µm and 383.26 ± 64.45 µm for the E. prostrata A and E. prostrata B dressings, respectively). The E. prostrata B dressings showed a higher percentage of weight increase in the first hour and a faster dehydration rate in the first 4 h. Furthermore, the E. prostrata dressings had a slightly acidic environment (5.28 ± 0.02 and 5.38 ± 0.02 for the E. prostrata A and E. prostrata B dressings at 48 h, respectively). MDPI 2023-05-02 /pmc/articles/PMC10222729/ /pubmed/37242467 http://dx.doi.org/10.3390/ph16050685 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Hasatsri, Sukhontha
Suthi, Jariya
Siriwut, Nattaporn
Charoensappakit, Onjira
Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin
title Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin
title_full Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin
title_fullStr Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin
title_full_unstemmed Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin
title_short Physical Properties and pH Environment of Foam Dressing Containing Eclipta prostrata Leaf Extract and Gelatin
title_sort physical properties and ph environment of foam dressing containing eclipta prostrata leaf extract and gelatin
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222729/
https://www.ncbi.nlm.nih.gov/pubmed/37242467
http://dx.doi.org/10.3390/ph16050685
work_keys_str_mv AT hasatsrisukhontha physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin
AT suthijariya physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin
AT siriwutnattaporn physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin
AT charoensappakitonjira physicalpropertiesandphenvironmentoffoamdressingcontainingecliptaprostrataleafextractandgelatin