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Polysaccharides—Naturally Occurring Immune Modulators

The prevention of disease and infection requires immune systems that operate effectively. This is accomplished by the elimination of infections and abnormal cells. Immune or biological therapy treats disease by either stimulating or inhibiting the immune system, dependent upon the circumstances. In...

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Autores principales: Murphy, Emma J., Fehrenbach, Gustavo Waltzer, Abidin, Ismin Zainol, Buckley, Ciara, Montgomery, Therese, Pogue, Robert, Murray, Patrick, Major, Ian, Rezoagli, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222865/
https://www.ncbi.nlm.nih.gov/pubmed/37242947
http://dx.doi.org/10.3390/polym15102373
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author Murphy, Emma J.
Fehrenbach, Gustavo Waltzer
Abidin, Ismin Zainol
Buckley, Ciara
Montgomery, Therese
Pogue, Robert
Murray, Patrick
Major, Ian
Rezoagli, Emanuele
author_facet Murphy, Emma J.
Fehrenbach, Gustavo Waltzer
Abidin, Ismin Zainol
Buckley, Ciara
Montgomery, Therese
Pogue, Robert
Murray, Patrick
Major, Ian
Rezoagli, Emanuele
author_sort Murphy, Emma J.
collection PubMed
description The prevention of disease and infection requires immune systems that operate effectively. This is accomplished by the elimination of infections and abnormal cells. Immune or biological therapy treats disease by either stimulating or inhibiting the immune system, dependent upon the circumstances. In plants, animals, and microbes, polysaccharides are abundant biomacromolecules. Due to the intricacy of their structure, polysaccharides may interact with and impact the immune response; hence, they play a crucial role in the treatment of several human illnesses. There is an urgent need for the identification of natural biomolecules that may prevent infection and treat chronic disease. This article addresses some of the naturally occurring polysaccharides of known therapeutic potential that have already been identified. This article also discusses extraction methods and immunological modulatory capabilities.
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spelling pubmed-102228652023-05-28 Polysaccharides—Naturally Occurring Immune Modulators Murphy, Emma J. Fehrenbach, Gustavo Waltzer Abidin, Ismin Zainol Buckley, Ciara Montgomery, Therese Pogue, Robert Murray, Patrick Major, Ian Rezoagli, Emanuele Polymers (Basel) Review The prevention of disease and infection requires immune systems that operate effectively. This is accomplished by the elimination of infections and abnormal cells. Immune or biological therapy treats disease by either stimulating or inhibiting the immune system, dependent upon the circumstances. In plants, animals, and microbes, polysaccharides are abundant biomacromolecules. Due to the intricacy of their structure, polysaccharides may interact with and impact the immune response; hence, they play a crucial role in the treatment of several human illnesses. There is an urgent need for the identification of natural biomolecules that may prevent infection and treat chronic disease. This article addresses some of the naturally occurring polysaccharides of known therapeutic potential that have already been identified. This article also discusses extraction methods and immunological modulatory capabilities. MDPI 2023-05-19 /pmc/articles/PMC10222865/ /pubmed/37242947 http://dx.doi.org/10.3390/polym15102373 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Murphy, Emma J.
Fehrenbach, Gustavo Waltzer
Abidin, Ismin Zainol
Buckley, Ciara
Montgomery, Therese
Pogue, Robert
Murray, Patrick
Major, Ian
Rezoagli, Emanuele
Polysaccharides—Naturally Occurring Immune Modulators
title Polysaccharides—Naturally Occurring Immune Modulators
title_full Polysaccharides—Naturally Occurring Immune Modulators
title_fullStr Polysaccharides—Naturally Occurring Immune Modulators
title_full_unstemmed Polysaccharides—Naturally Occurring Immune Modulators
title_short Polysaccharides—Naturally Occurring Immune Modulators
title_sort polysaccharides—naturally occurring immune modulators
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222865/
https://www.ncbi.nlm.nih.gov/pubmed/37242947
http://dx.doi.org/10.3390/polym15102373
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