Cargando…

Poly(I:C) Induces Distinct Liver Cell Type-Specific Responses in Hepatitis B Virus-Transgenic Mice In Vitro, but Fails to Induce These Signals In Vivo

Immunopathology in hepatitis B virus (HBV) infection is driven by innate and adaptive immunity. Whether the hepatitis B surface antigen (HBsAg) affects hepatic antiviral signalling was investigated in HBV-transgenic mouse models that either accumulate (Alb/HBs, Tg[Alb1HBV]Bri44), lack (Tg1.4HBV-s-mu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schefczyk, Stefan, Luo, Xufeng, Liang, Yaojie, Trippler, Martin, Lu, Mengji, Wedemeyer, Heiner, Schmidt, Hartmut H., Broering, Ruth
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222874/ https://www.ncbi.nlm.nih.gov/pubmed/37243287 http://dx.doi.org/10.3390/v15051203

Ejemplares similares

Hippo Pathway Counter-Regulates Innate Immunity in Hepatitis B Virus Infection
por: Luo, Xufeng, et al.
Publicado: (2021)

Antiviral Toll-like Receptor Signaling in Non-Parenchymal Liver Cells Is Restricted to TLR3
por: Werner, Melanie, et al.
Publicado: (2022)

Promyelocytic leukemia protein deficiency leads to spontaneous formation of liver tumors in hepatitis C virus transgenic mice
por: Straub, Katja, et al.
Publicado: (2019)

Controversial: Early Innate Responses to Hepatitis B Virus Infection, an Explanation for Viral Persistence?
por: Broering, Ruth, et al.
Publicado: (2020)

Exploiting poly(I:C) to induce cancer cell apoptosis
por: Bianchi, Francesca, et al.
Publicado: (2017)

Pathological Role of Interleukin-17 in Poly I:C-Induced Hepatitis
por: He, Jianqin, et al.
Publicado: (2013)

In Vivo Mouse Models for Hepatitis B Virus Infection and Their Application
por: Du, Yanqin, et al.
Publicado: (2021)

Interferon Alpha Induces Cellular Autophagy and Modulates Hepatitis B Virus Replication
por: Li, Jia, et al.
Publicado: (2022)

TLR3 Agonist Poly-IC Induces IL-33 and Promotes Myelin Repair
por: Natarajan, Chandramohan, et al.
Publicado: (2016)

Comprehensive evaluation of poly(I:C) induced inflammatory response in an airway epithelial model
por: Lever, Amanda R, et al.
Publicado: (2015)

Inhibition of Poly(I:C)-Induced Inflammation by Salvianolic Acid A in Skin Keratinocytes
por: Zhang, Qing-Ling, et al.
Publicado: (2019)

poly(I:C) synergizes with proteasome inhibitors to induce apoptosis in cervical cancer cells
por: Meng, Xueqiong, et al.
Publicado: (2022)

Polysaccharide of Radix Pseudostellariae Improves Chronic Fatigue Syndrome Induced by Poly I:C in Mice
por: Sheng, Rong, et al.
Publicado: (2011)

Inhibition of poly(I:C)–induced matrix metalloproteinase expression in human corneal fibroblasts by triptolide
por: Kimura, Kazuhiro, et al.
Publicado: (2011)

Poly I:C induces collective migration of HaCaT keratinocytes via IL-8
por: Takada, Kazuhide, et al.
Publicado: (2017)

HDAC6 Mediates Poly (I:C)-Induced TBK1 and Akt Phosphorylation in Macrophages
por: Wang, Yan, et al.
Publicado: (2020)

ORMDL3 regulates poly I:C induced inflammatory responses in airway epithelial cells
por: Laura, Gemma, et al.
Publicado: (2021)

Immunotherapeutic effects of intratumoral nanoplexed poly I:C
por: Aznar, M. Angela, et al.
Publicado: (2019)

Poly I:C enhances cycloheximide-induced apoptosis of tumor cells through TLR3 pathway
por: Jiang, Qun, et al.
Publicado: (2008)

Poly I:C adjuvanted inactivated swine influenza vaccine induces heterologous protective immunity in pigs
por: Thomas, Milton, et al.
Publicado: (2015)

Clozapine Prevents Poly (I:C) Induced Inflammation by Modulating NLRP3 Pathway in Microglial Cells
por: V. Giridharan, Vijayasree, et al.
Publicado: (2020)

Soluble TNF-like weak inducer of apoptosis (TWEAK) enhances poly(I:C)-induced RIPK1-mediated necroptosis
por: Anany, Mohamed A., et al.
Publicado: (2018)

Distinct and complementary functions of MDA5 and TLR3 in poly(I:C)-mediated activation of mouse NK cells
por: McCartney, Stephen, et al.
Publicado: (2009)

TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles
por: Frank-Bertoncelj, Mojca, et al.
Publicado: (2018)

Long-term activation of TLR3 by Poly(I:C) induces inflammation and impairs lung function in mice
por: Stowell, Nicole C, et al.
Publicado: (2009)

Pathogenic Mouse Hepatitis Virus or Poly(I:C) Induce IL-33 in Hepatocytes in Murine Models of Hepatitis
por: Arshad, Muhammad Imran, et al.
Publicado: (2013)

Poly(I:C) induces controlled release of IL-36γ from keratinocytes in the absence of cell death
por: Rana, Ali A., et al.
Publicado: (2015)

Engagement of Fas on Macrophages Modulates Poly I:C Induced Cytokine Production with Specific Enhancement of IP-10
por: Lyons, Caitriona, et al.
Publicado: (2015)

Poly(I:C) stimulation is superior than Imiquimod to induce the antitumoral functional profile of tumor‐conditioned macrophages
por: Maeda, Akihiro, et al.
Publicado: (2019)

Andrographolide sulfate inhibited NF-κB activation and alleviated pneumonia induced by poly I:C in mice
por: Cui, Jian, et al.
Publicado: (2020)

The IL-17 receptor IL-17RE mediates polyIC-induced exacerbation of experimental allergic asthma
por: Vella, Giovanna, et al.
Publicado: (2020)

Interleukin-38 ameliorates poly(I:C) induced lung inflammation: therapeutic implications in respiratory viral infections
por: Gao, Xun, et al.
Publicado: (2021)

Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells
por: Nakazono, Akira, et al.
Publicado: (2021)

Poly(I:C) transfection induces a pro-inflammatory cascade in murine mammary carcinoma and fibrosarcoma cells
por: Sales Conniff, A, et al.
Publicado: (2022)

Nicotinamide mononucleotide (NMN) alleviates the poly(I:C)-induced inflammatory response in human primary cell cultures
por: Sano, Hitomi, et al.
Publicado: (2023)

HBeAg induces liver sinusoidal endothelial cell activation to promote intrahepatic CD8 T cell immunity and HBV clearance
por: Xie, Xiaohong, et al.
Publicado: (2021)

Innate immune responses and neuroepithelial degeneration and regeneration in the mouse olfactory mucosa induced by intranasal administration of Poly(I:C)
por: Kanaya, Kaori, et al.
Publicado: (2014)

Inactivated Eyedrop Influenza Vaccine Adjuvanted with Poly(I:C) Is Safe and Effective for Inducing Protective Systemic and Mucosal Immunity
por: Kim, Eun-Do, et al.
Publicado: (2015)

Isoflavones inhibit poly(I:C)-induced serum, brain, and skin inflammatory mediators - relevance to chronic fatigue syndrome
por: Vasiadi, Magdalini, et al.
Publicado: (2014)

Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5
por: Huang, Li-Yun, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_aul0j2q14r16j9bdhod763vff8