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Donepezil Brain and Blood Pharmacokinetic Modeling after Nasal Film and Oral Solution Administration in Mice

Intranasal delivery is a non-invasive mode of administration, gaining popularity due to its potential for targeted delivery to the brain. The anatomic connection of the nasal cavity with the central nervous system (CNS) is based on two nerves: olfactory and trigeminal. Moreover, the high vasculature...

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Detalles Bibliográficos
Autores principales:	Kaikousidis, Christos, Papakyriakopoulou, Paraskevi, Dokoumetzidis, Aristides, Valsami, Georgia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10222980/ https://www.ncbi.nlm.nih.gov/pubmed/37242651 http://dx.doi.org/10.3390/pharmaceutics15051409

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