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Voltage-Gated Sodium Channel Dysfunctions in Neurological Disorders

The pore-forming subunits (α subunits) of voltage-gated sodium channels (VGSC) are encoded in humans by a family of nine highly conserved genes. Among them, SCN1A, SCN2A, SCN3A, and SCN8A are primarily expressed in the central nervous system. The encoded proteins Nav1.1, Nav1.2, Nav1.3, and Nav1.6,...

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Detalles Bibliográficos
Autores principales:	Barbieri, Raffaella, Nizzari, Mario, Zanardi, Ilaria, Pusch, Michael, Gavazzo, Paola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223093/ https://www.ncbi.nlm.nih.gov/pubmed/37240836 http://dx.doi.org/10.3390/life13051191

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