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Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies

Background and Objectives: Overprescribing of antibiotics is one of the important contributors of antimicrobial resistance globally. A high proportion of antibiotics prescribed in community settings are unnecessary or inappropriate. This study assesses the prescribing practices and factors related t...

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Autores principales: Rabbani, Syed Arman, Sridhar, Sathvik B., Safdar, Maryam, Rao, Padma G. M., Jaber, Ammar Ali Saleh, AlAhmad, Mohammad M., Shaar, Khaled, Emad, Israa, Azim, Muhammad Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223119/
https://www.ncbi.nlm.nih.gov/pubmed/37241075
http://dx.doi.org/10.3390/medicina59050843
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author Rabbani, Syed Arman
Sridhar, Sathvik B.
Safdar, Maryam
Rao, Padma G. M.
Jaber, Ammar Ali Saleh
AlAhmad, Mohammad M.
Shaar, Khaled
Emad, Israa
Azim, Muhammad Abdul
author_facet Rabbani, Syed Arman
Sridhar, Sathvik B.
Safdar, Maryam
Rao, Padma G. M.
Jaber, Ammar Ali Saleh
AlAhmad, Mohammad M.
Shaar, Khaled
Emad, Israa
Azim, Muhammad Abdul
author_sort Rabbani, Syed Arman
collection PubMed
description Background and Objectives: Overprescribing of antibiotics is one of the important contributors of antimicrobial resistance globally. A high proportion of antibiotics prescribed in community settings are unnecessary or inappropriate. This study assesses the prescribing practices and factors related to antibiotic prescribing in community pharmacies in United Arab Emirates (UAE). Materials and Methods: A cross-sectional study utilizing a quantitative approach was carried out in the community pharmacies of Ras Al Khaimah (RAK), UAE. Six hundred and thirty prescription encounters from 21 randomly selected community pharmacies were investigated using World Health Organization (WHO) core prescribing indicators. Factors related to antibiotic prescribing were identified using logistic regression analyses. Results: In 630 prescription encounters, a total of 1814 drugs were prescribed. Out of these, the most commonly prescribed drug class was antibiotics (43.8% prescriptions) and the antibiotic was amoxicillin/clavulanic-acid (22.4%). The average number of drugs per prescription was 2.88, which was higher than the WHO recommended value of 1.6–1.8. In addition, more than half of the prescriptions (58.6%) had drugs by generic names and the majority of the drugs prescribed (83.8%) were from the essential drug list, which were lower than the optimal values of 100%. The majority of the antibiotics prescribed in the study were from the WHO’s Access group antibiotics. Multivariable logistic regression analysis identified patient age (children—OR: 7.40, 95% CI: 2.32–23.62, p = 0.001 and adolescent—OR: 5.86, 95% CI: 1.57–21.86, p = 0.008), prescriber qualification as general practitioner (OR: 1.84, 95% CI:1.30–2.60, p = 0.001), and number of drugs per prescription (OR: 3.51, 95% CI: 1.98–6.21, p < 0.001) as independent factors associated with antibiotic prescribing. Conclusions: This study reveals considerable variations from the WHO recommendations for the different prescribing indicators in the community pharmacies of RAK, UAE. In addition, the study reports overprescribing of antibiotics in the community setting, indicating the need for interventions to promote rational use of antibiotics in a community setting.
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spelling pubmed-102231192023-05-28 Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies Rabbani, Syed Arman Sridhar, Sathvik B. Safdar, Maryam Rao, Padma G. M. Jaber, Ammar Ali Saleh AlAhmad, Mohammad M. Shaar, Khaled Emad, Israa Azim, Muhammad Abdul Medicina (Kaunas) Article Background and Objectives: Overprescribing of antibiotics is one of the important contributors of antimicrobial resistance globally. A high proportion of antibiotics prescribed in community settings are unnecessary or inappropriate. This study assesses the prescribing practices and factors related to antibiotic prescribing in community pharmacies in United Arab Emirates (UAE). Materials and Methods: A cross-sectional study utilizing a quantitative approach was carried out in the community pharmacies of Ras Al Khaimah (RAK), UAE. Six hundred and thirty prescription encounters from 21 randomly selected community pharmacies were investigated using World Health Organization (WHO) core prescribing indicators. Factors related to antibiotic prescribing were identified using logistic regression analyses. Results: In 630 prescription encounters, a total of 1814 drugs were prescribed. Out of these, the most commonly prescribed drug class was antibiotics (43.8% prescriptions) and the antibiotic was amoxicillin/clavulanic-acid (22.4%). The average number of drugs per prescription was 2.88, which was higher than the WHO recommended value of 1.6–1.8. In addition, more than half of the prescriptions (58.6%) had drugs by generic names and the majority of the drugs prescribed (83.8%) were from the essential drug list, which were lower than the optimal values of 100%. The majority of the antibiotics prescribed in the study were from the WHO’s Access group antibiotics. Multivariable logistic regression analysis identified patient age (children—OR: 7.40, 95% CI: 2.32–23.62, p = 0.001 and adolescent—OR: 5.86, 95% CI: 1.57–21.86, p = 0.008), prescriber qualification as general practitioner (OR: 1.84, 95% CI:1.30–2.60, p = 0.001), and number of drugs per prescription (OR: 3.51, 95% CI: 1.98–6.21, p < 0.001) as independent factors associated with antibiotic prescribing. Conclusions: This study reveals considerable variations from the WHO recommendations for the different prescribing indicators in the community pharmacies of RAK, UAE. In addition, the study reports overprescribing of antibiotics in the community setting, indicating the need for interventions to promote rational use of antibiotics in a community setting. MDPI 2023-04-27 /pmc/articles/PMC10223119/ /pubmed/37241075 http://dx.doi.org/10.3390/medicina59050843 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Rabbani, Syed Arman
Sridhar, Sathvik B.
Safdar, Maryam
Rao, Padma G. M.
Jaber, Ammar Ali Saleh
AlAhmad, Mohammad M.
Shaar, Khaled
Emad, Israa
Azim, Muhammad Abdul
Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies
title Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies
title_full Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies
title_fullStr Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies
title_full_unstemmed Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies
title_short Assessment of Prescribing Practices and Factors Related to Antibiotic Prescribing in Community Pharmacies
title_sort assessment of prescribing practices and factors related to antibiotic prescribing in community pharmacies
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223119/
https://www.ncbi.nlm.nih.gov/pubmed/37241075
http://dx.doi.org/10.3390/medicina59050843
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