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Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method

In positron emission tomography (PET), parallax errors degrade spatial resolution. The depth of interaction (DOI) information provides the position in the depth of the scintillator interacting with the γ-rays, thus reducing parallax errors. A previous study developed a Peak-to-Charge discrimination...

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Autores principales: Miyata, Kento, Ogawara, Ryo, Ishikawa, Masayori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223191/
https://www.ncbi.nlm.nih.gov/pubmed/37430498
http://dx.doi.org/10.3390/s23104584
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author Miyata, Kento
Ogawara, Ryo
Ishikawa, Masayori
author_facet Miyata, Kento
Ogawara, Ryo
Ishikawa, Masayori
author_sort Miyata, Kento
collection PubMed
description In positron emission tomography (PET), parallax errors degrade spatial resolution. The depth of interaction (DOI) information provides the position in the depth of the scintillator interacting with the γ-rays, thus reducing parallax errors. A previous study developed a Peak-to-Charge discrimination (PQD), which can separate spontaneous alpha decay in LaBr(3):Ce. Since decay constant of GSO:Ce depends on Ce concentration, the PQD is expected to discriminate GSO:Ce scintillators with different Ce concentration. In this study, the PQD-based DOI detector system was developed, which can be processed online and implemented in PET. A detector was composed of four layers of GSO:Ce crystals and a PS-PMT. The four crystals were obtained from both the top and bottom of ingots with a nominal Ce concentration of 0.5 mol% and 1.5 mol%. The PQD was implemented on the Xilinx Zynq-7000 SoC board with 8ch Flash ADC to gain real-time processing, flexibility, and expandability. The results showed that the mean Figure of Merits in 1D between four scintillators are 1.5, 0.99, 0.91 for layers between 1st–2nd, 2nd–3rd, and 3rd–4th respectively, and the mean Error Rate in 1D between four scintillators are 3.50%, 2.96%, 13.3%, and 1.88% for layers 1, 2, 3, and 4, respectively. In addition, the introduction of the 2D PQDs resulted in the mean Figure of Merits in 2D greater than 0.9 and the mean Error Rate in 2D less than 3% in all layers.
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spelling pubmed-102231912023-05-28 Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method Miyata, Kento Ogawara, Ryo Ishikawa, Masayori Sensors (Basel) Article In positron emission tomography (PET), parallax errors degrade spatial resolution. The depth of interaction (DOI) information provides the position in the depth of the scintillator interacting with the γ-rays, thus reducing parallax errors. A previous study developed a Peak-to-Charge discrimination (PQD), which can separate spontaneous alpha decay in LaBr(3):Ce. Since decay constant of GSO:Ce depends on Ce concentration, the PQD is expected to discriminate GSO:Ce scintillators with different Ce concentration. In this study, the PQD-based DOI detector system was developed, which can be processed online and implemented in PET. A detector was composed of four layers of GSO:Ce crystals and a PS-PMT. The four crystals were obtained from both the top and bottom of ingots with a nominal Ce concentration of 0.5 mol% and 1.5 mol%. The PQD was implemented on the Xilinx Zynq-7000 SoC board with 8ch Flash ADC to gain real-time processing, flexibility, and expandability. The results showed that the mean Figure of Merits in 1D between four scintillators are 1.5, 0.99, 0.91 for layers between 1st–2nd, 2nd–3rd, and 3rd–4th respectively, and the mean Error Rate in 1D between four scintillators are 3.50%, 2.96%, 13.3%, and 1.88% for layers 1, 2, 3, and 4, respectively. In addition, the introduction of the 2D PQDs resulted in the mean Figure of Merits in 2D greater than 0.9 and the mean Error Rate in 2D less than 3% in all layers. MDPI 2023-05-09 /pmc/articles/PMC10223191/ /pubmed/37430498 http://dx.doi.org/10.3390/s23104584 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Miyata, Kento
Ogawara, Ryo
Ishikawa, Masayori
Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method
title Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method
title_full Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method
title_fullStr Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method
title_full_unstemmed Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method
title_short Improvement of Crystal Identification Accuracy for Depth-of-Interaction Detector System with Peak-to-Charge Discrimination Method
title_sort improvement of crystal identification accuracy for depth-of-interaction detector system with peak-to-charge discrimination method
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223191/
https://www.ncbi.nlm.nih.gov/pubmed/37430498
http://dx.doi.org/10.3390/s23104584
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