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Intrinsically Disordered Synthetic Polymers in Biomedical Applications
In biology and medicine, intrinsically disordered synthetic polymers bio-mimicking intrinsically disordered proteins, which lack stable three-dimensional structures, possess high structural/conformational flexibility. They are prone to self-organization and can be extremely useful in various biomedi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223235/ https://www.ncbi.nlm.nih.gov/pubmed/37242981 http://dx.doi.org/10.3390/polym15102406 |
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author | Yuce-Erarslan, Elif Domb, Abraham (Avi) J. Kasem, Haytam Uversky, Vladimir N. Coskuner-Weber, Orkid |
author_facet | Yuce-Erarslan, Elif Domb, Abraham (Avi) J. Kasem, Haytam Uversky, Vladimir N. Coskuner-Weber, Orkid |
author_sort | Yuce-Erarslan, Elif |
collection | PubMed |
description | In biology and medicine, intrinsically disordered synthetic polymers bio-mimicking intrinsically disordered proteins, which lack stable three-dimensional structures, possess high structural/conformational flexibility. They are prone to self-organization and can be extremely useful in various biomedical applications. Among such applications, intrinsically disordered synthetic polymers can have potential usage in drug delivery, organ transplantation, artificial organ design, and immune compatibility. The designing of new syntheses and characterization mechanisms is currently required to provide the lacking intrinsically disordered synthetic polymers for biomedical applications bio-mimicked using intrinsically disordered proteins. Here, we present our strategies for designing intrinsically disordered synthetic polymers for biomedical applications based on bio-mimicking intrinsically disordered proteins. |
format | Online Article Text |
id | pubmed-10223235 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102232352023-05-28 Intrinsically Disordered Synthetic Polymers in Biomedical Applications Yuce-Erarslan, Elif Domb, Abraham (Avi) J. Kasem, Haytam Uversky, Vladimir N. Coskuner-Weber, Orkid Polymers (Basel) Review In biology and medicine, intrinsically disordered synthetic polymers bio-mimicking intrinsically disordered proteins, which lack stable three-dimensional structures, possess high structural/conformational flexibility. They are prone to self-organization and can be extremely useful in various biomedical applications. Among such applications, intrinsically disordered synthetic polymers can have potential usage in drug delivery, organ transplantation, artificial organ design, and immune compatibility. The designing of new syntheses and characterization mechanisms is currently required to provide the lacking intrinsically disordered synthetic polymers for biomedical applications bio-mimicked using intrinsically disordered proteins. Here, we present our strategies for designing intrinsically disordered synthetic polymers for biomedical applications based on bio-mimicking intrinsically disordered proteins. MDPI 2023-05-22 /pmc/articles/PMC10223235/ /pubmed/37242981 http://dx.doi.org/10.3390/polym15102406 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Yuce-Erarslan, Elif Domb, Abraham (Avi) J. Kasem, Haytam Uversky, Vladimir N. Coskuner-Weber, Orkid Intrinsically Disordered Synthetic Polymers in Biomedical Applications |
title | Intrinsically Disordered Synthetic Polymers in Biomedical Applications |
title_full | Intrinsically Disordered Synthetic Polymers in Biomedical Applications |
title_fullStr | Intrinsically Disordered Synthetic Polymers in Biomedical Applications |
title_full_unstemmed | Intrinsically Disordered Synthetic Polymers in Biomedical Applications |
title_short | Intrinsically Disordered Synthetic Polymers in Biomedical Applications |
title_sort | intrinsically disordered synthetic polymers in biomedical applications |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223235/ https://www.ncbi.nlm.nih.gov/pubmed/37242981 http://dx.doi.org/10.3390/polym15102406 |
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