Central Nervous System Histoplasmosis: An Updated Insight

Histoplasmosis is one of the systemic mycoses that can involve the Central Nervous System (CNS), and it is caused by the dimorphic ascomycete species of the Histoplasma capsulatum complex. Once in the CNS, this pathogen causes life-threatening injuries that are associated with clinical manifestation...

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Autores principales: Ramírez, José Antonio, Reyes-Montes, María del Rocío, Rodríguez-Arellanes, Gabriela, Pérez-Torres, Armando, Taylor, Maria Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223317/
https://www.ncbi.nlm.nih.gov/pubmed/37242351
http://dx.doi.org/10.3390/pathogens12050681
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author Ramírez, José Antonio
Reyes-Montes, María del Rocío
Rodríguez-Arellanes, Gabriela
Pérez-Torres, Armando
Taylor, Maria Lucia
author_facet Ramírez, José Antonio
Reyes-Montes, María del Rocío
Rodríguez-Arellanes, Gabriela
Pérez-Torres, Armando
Taylor, Maria Lucia
author_sort Ramírez, José Antonio
collection PubMed
description Histoplasmosis is one of the systemic mycoses that can involve the Central Nervous System (CNS), and it is caused by the dimorphic ascomycete species of the Histoplasma capsulatum complex. Once in the CNS, this pathogen causes life-threatening injuries that are associated with clinical manifestations of meningitis, focal lesions (abscesses, histoplasmomas), and spinal cord injuries. The present review provides updated data and highlights a particular vision regarding this mycosis and its causative agent, as well as its epidemiology, clinical forms, pathogenesis, diagnosis, and therapy, focusing on the CNS.
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spelling pubmed-102233172023-05-28 Central Nervous System Histoplasmosis: An Updated Insight Ramírez, José Antonio Reyes-Montes, María del Rocío Rodríguez-Arellanes, Gabriela Pérez-Torres, Armando Taylor, Maria Lucia Pathogens Perspective Histoplasmosis is one of the systemic mycoses that can involve the Central Nervous System (CNS), and it is caused by the dimorphic ascomycete species of the Histoplasma capsulatum complex. Once in the CNS, this pathogen causes life-threatening injuries that are associated with clinical manifestations of meningitis, focal lesions (abscesses, histoplasmomas), and spinal cord injuries. The present review provides updated data and highlights a particular vision regarding this mycosis and its causative agent, as well as its epidemiology, clinical forms, pathogenesis, diagnosis, and therapy, focusing on the CNS. MDPI 2023-05-05 /pmc/articles/PMC10223317/ /pubmed/37242351 http://dx.doi.org/10.3390/pathogens12050681 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Perspective
Ramírez, José Antonio
Reyes-Montes, María del Rocío
Rodríguez-Arellanes, Gabriela
Pérez-Torres, Armando
Taylor, Maria Lucia
Central Nervous System Histoplasmosis: An Updated Insight
title Central Nervous System Histoplasmosis: An Updated Insight
title_full Central Nervous System Histoplasmosis: An Updated Insight
title_fullStr Central Nervous System Histoplasmosis: An Updated Insight
title_full_unstemmed Central Nervous System Histoplasmosis: An Updated Insight
title_short Central Nervous System Histoplasmosis: An Updated Insight
title_sort central nervous system histoplasmosis: an updated insight
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223317/
https://www.ncbi.nlm.nih.gov/pubmed/37242351
http://dx.doi.org/10.3390/pathogens12050681
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