The Flavonoid Agathisflavone Directs Brain Microglia/Macrophages to a Neuroprotective Anti-Inflammatory and Antioxidant State via Regulation of NLRP3 Inflammasome

Agathisflavone, purified from Cenostigma pyramidale (Tul.) has been shown to be neuroprotective in in vitro models of glutamate-induced excitotoxicity and inflammatory damage. However, the potential role of microglial regulation by agathisflavone in these neuroprotective effects is unclear. Here we...

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Detalles Bibliográficos
Autores principales: dos Santos, Balbino Lino, dos Santos, Cleonice Creusa, Soares, Janaina R. P., da Silva, Karina C., de Oliveira, Juciele Valeria R., Pereira, Gabriele S., de Araújo, Fillipe M., Costa, Maria de Fátima D., David, Jorge Mauricio, da Silva, Victor Diogenes A., Butt, Arthur Morgan, Costa, Silvia Lima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223401/
https://www.ncbi.nlm.nih.gov/pubmed/37242652
http://dx.doi.org/10.3390/pharmaceutics15051410

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