Immunisation with Transgenic L. tarentolae Expressing Gamma Glutamyl Cysteine Synthetase from Pathogenic Leishmania Species Protected against L. major and L. donovani Infection in a Murine Model

Leishmaniasis is a protozoan disease responsible for significant morbidity and mortality. There is no recommended vaccine to protect against infection. In this study, transgenic Leishmania tarentolae expressing gamma glutamyl cysteine synthetase (γGCS) from three pathogenic species were produced and...

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Detalles Bibliográficos
Autores principales: Topuz Ata, Derya, Hussain, Muattaz, Jones, Michael, Best, Jonathan, Wiese, Martin, Carter, Katharine Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223578/
https://www.ncbi.nlm.nih.gov/pubmed/37317296
http://dx.doi.org/10.3390/microorganisms11051322

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