Structural Congeners of Izenamides Responsible for Cathepsin D Inhibition: Insights from Synthesis-Derived Elucidation †

This study aimed to elucidate the structural congeners of natural izenamides A, B, and C (1–3) responsible for cathepsin D (CTSD) inhibition. Structurally modified izenamides were synthesized and biologically evaluated, and their biologically important core structures were identified. We confirmed t...

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Detalles Bibliográficos
Autores principales: Kim, Hyun Su, Kong, Hyejin, Kim, Taewoo, Lim, Changjin, Lee, Seungbeom, Kim, Seok-Ho, Suh, Young-Ger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223608/
https://www.ncbi.nlm.nih.gov/pubmed/37233475
http://dx.doi.org/10.3390/md21050281

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223608/
https://www.ncbi.nlm.nih.gov/pubmed/37233475
http://dx.doi.org/10.3390/md21050281

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