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Synthetic Routes to Approved Drugs Containing a Spirocycle †

The use of spirocycles in drug discovery and medicinal chemistry has been booming in the last two decades. This has clearly translated into the landscape of approved drugs. Among two dozen clinically used medicines containing a spirocycle, 50% have been approved in the 21st century. The present revi...

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Detalles Bibliográficos
Autores principales: Moshnenko, Nazar, Kazantsev, Alexander, Chupakhin, Evgeny, Bakulina, Olga, Dar’in, Dmitry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223694/
https://www.ncbi.nlm.nih.gov/pubmed/37241950
http://dx.doi.org/10.3390/molecules28104209