Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms

Gut microbiota is closely related to human health and disease because, together with their metabolites, gut microbiota maintain normal intestinal peristalsis. The use of antibiotics or opioid anesthetics, or both, during surgical procedures can lead to dysbiosis and affect intestinal motility; howev...

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Autores principales: Ma, TianRong, Xue, XiaoLei, Tian, Hui, Zhou, XinXiu, Wang, JunKe, Zhao, ZhiWen, Wang, MingFei, Song, JiYuan, Feng, RenXiang, Li, Leping, Jing, Changqing, Tian, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223893/
https://www.ncbi.nlm.nih.gov/pubmed/37237321
http://dx.doi.org/10.1186/s12967-023-04215-2
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author Ma, TianRong
Xue, XiaoLei
Tian, Hui
Zhou, XinXiu
Wang, JunKe
Zhao, ZhiWen
Wang, MingFei
Song, JiYuan
Feng, RenXiang
Li, Leping
Jing, Changqing
Tian, Feng
author_facet Ma, TianRong
Xue, XiaoLei
Tian, Hui
Zhou, XinXiu
Wang, JunKe
Zhao, ZhiWen
Wang, MingFei
Song, JiYuan
Feng, RenXiang
Li, Leping
Jing, Changqing
Tian, Feng
author_sort Ma, TianRong
collection PubMed
description Gut microbiota is closely related to human health and disease because, together with their metabolites, gut microbiota maintain normal intestinal peristalsis. The use of antibiotics or opioid anesthetics, or both, during surgical procedures can lead to dysbiosis and affect intestinal motility; however, the underlying mechanisms are not fully known. This review aims to discuss the effect of gut microbiota and their metabolites on postoperative intestinal motility, focusing on regulating the enteric nervous system, 5-hydroxytryptamine neurotransmitter, and aryl hydrocarbon receptor.
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spelling pubmed-102238932023-05-28 Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms Ma, TianRong Xue, XiaoLei Tian, Hui Zhou, XinXiu Wang, JunKe Zhao, ZhiWen Wang, MingFei Song, JiYuan Feng, RenXiang Li, Leping Jing, Changqing Tian, Feng J Transl Med Review Gut microbiota is closely related to human health and disease because, together with their metabolites, gut microbiota maintain normal intestinal peristalsis. The use of antibiotics or opioid anesthetics, or both, during surgical procedures can lead to dysbiosis and affect intestinal motility; however, the underlying mechanisms are not fully known. This review aims to discuss the effect of gut microbiota and their metabolites on postoperative intestinal motility, focusing on regulating the enteric nervous system, 5-hydroxytryptamine neurotransmitter, and aryl hydrocarbon receptor. BioMed Central 2023-05-26 /pmc/articles/PMC10223893/ /pubmed/37237321 http://dx.doi.org/10.1186/s12967-023-04215-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Ma, TianRong
Xue, XiaoLei
Tian, Hui
Zhou, XinXiu
Wang, JunKe
Zhao, ZhiWen
Wang, MingFei
Song, JiYuan
Feng, RenXiang
Li, Leping
Jing, Changqing
Tian, Feng
Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms
title Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms
title_full Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms
title_fullStr Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms
title_full_unstemmed Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms
title_short Effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms
title_sort effect of the gut microbiota and their metabolites on postoperative intestinal motility and its underlying mechanisms
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223893/
https://www.ncbi.nlm.nih.gov/pubmed/37237321
http://dx.doi.org/10.1186/s12967-023-04215-2
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