Hsp70-Bim interaction facilitates mitophagy by recruiting parkin and TOMM20 into a complex

BACKGROUND: For cancer therapy, the identification of both selective autophagy targets and small molecules that specifically regulate autophagy is greatly needed. Heat shock protein 70 (Hsp70) is a recently discovered BH3 receptor that forms a protein‒protein interaction (PPI) with Bcl-2-interacting...

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Detalles Bibliográficos
Autores principales: Song, Ting, Yin, Fangkui, Wang, Ziqian, Zhang, Hong, Liu, Peng, Guo, Yafei, Tang, Yao, Zhang, Zhichao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223935/
https://www.ncbi.nlm.nih.gov/pubmed/37237369
http://dx.doi.org/10.1186/s11658-023-00458-5

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