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Histone lysine methyltransferase SMYD3 promotes oral squamous cell carcinoma tumorigenesis via H3K4me3-mediated HMGA2 transcription

BACKGROUND: Epigenetic dysregulation is essential to the tumorigenesis of oral squamous cell carcinoma (OSCC). SET and MYND domain-containing protein 3 (SMYD3), a histone lysine methyltransferase, is implicated in gene transcription regulation and tumor development. However, the roles of SMYD3 in OS...

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Detalles Bibliográficos
Autores principales: Yang, Zongcheng, Liu, Fen, Li, Zongkai, Liu, Nianping, Yao, Xinfeng, Zhou, Yu, Zhang, Liyu, Jiang, Pan, Liu, Honghong, Kong, Lingming, Lang, Chuandong, Xu, Xin, Jia, Jihui, Nakajima, Takahito, Gu, Wenchao, Zheng, Lixin, Zhang, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223939/
https://www.ncbi.nlm.nih.gov/pubmed/37237385
http://dx.doi.org/10.1186/s13148-023-01506-9