In Silico and In Vitro Evaluation of Some Amidine Derivatives as Hit Compounds towards Development of Inhibitors against Coronavirus Diseases

Coronaviruses, including SARS-CoV-2, SARS-CoV, MERS-CoV and influenza A virus, require the host proteases to mediate viral entry into cells. Rather than targeting the continuously mutating viral proteins, targeting the conserved host-based entry mechanism could offer advantages. Nafamostat and camos...

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Detalles Bibliográficos
Autores principales: Hassan, Ahmed H. E., El-Sayed, Selwan M., Yamamoto, Mizuki, Gohda, Jin, Matsumoto, Takehisa, Shirouzu, Mikako, Inoue, Jun-ichiro, Kawaguchi, Yasushi, Mansour, Reem M. A., Anvari, Abtin, Farahat, Abdelbasset A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223987/
https://www.ncbi.nlm.nih.gov/pubmed/37243257
http://dx.doi.org/10.3390/v15051171

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