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The Mineralocorticoid Receptor on Smooth Muscle Cells Promotes Tacrolimus-Induced Renal Injury in Mice

Tacrolimus (Tac) is a calcineurin inhibitor commonly used as an immunosuppressor after solid organ transplantation. However, Tac may induce hypertension, nephrotoxicity, and an increase in aldosterone levels. The activation of the mineralocorticoid receptor (MR) is related to the proinflammatory sta...

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Detalles Bibliográficos
Autores principales:	Figueroa, Stefanny M., Bertocchio, Jean-Philippe, Nakamura, Toshifumi, El-Moghrabi, Soumaya, Jaisser, Frédéric, Amador, Cristián A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10223994/ https://www.ncbi.nlm.nih.gov/pubmed/37242615 http://dx.doi.org/10.3390/pharmaceutics15051373

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