Cargando…

Arylimidamides Have Potential for Chemoprophylaxis against Blood-Transmitted Chagas Disease

Chagas disease (CD) affects over 6 million people worldwide and can be transmitted iatrogenically. Crystal violet (CV) was previously used for pathogen reduction but has harmful side-effects. In the present study, three arylimidamides (AIAs) and CV were used to sterilize mice blood samples experimen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Timm, Bruno Lisboa, da Gama, Aline Nefertiti Silva, Batista, Marcos Meuser, Batista, Denise da Gama Jaén, Boykin, David W., De Koning, Harry P., Correia Soeiro, Maria de Nazaré
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224031/ https://www.ncbi.nlm.nih.gov/pubmed/37242371 http://dx.doi.org/10.3390/pathogens12050701

Ejemplares similares

Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection
por: da Silva, Cristiane França, et al.
Publicado: (2017)

In Vitro and In Vivo Investigation of the Efficacy of Arylimidamide DB1831 and Its Mesylated Salt Form - DB1965 - against Trypanosoma cruzi Infection
por: da Silva, Cristiane França, et al.
Publicado: (2012)

Combined Treatment of Heterocyclic Analogues and Benznidazole upon Trypanosoma cruzi In Vivo
por: Batista, Denise da Gama Jaén, et al.
Publicado: (2011)

The Impact of the CTHRSSVVC Peptide Upon Experimental Models of Trypanosoma cruzi Infection
por: Leite, Gabriela Rodrigues, et al.
Publicado: (2022)

Synthesis and pharmacological evaluation of mono-arylimidamides as antileishmanial agents
por: Zhu, Xiaohua, et al.
Publicado: (2016)

Efficacy of sertraline against Trypanosoma cruzi: an in vitro and in silico study
por: Ferreira, Daiane Dias, et al.
Publicado: (2018)

Overexpression of TcNTPDase-1 Gene Increases Infectivity in Mice Infected with Trypanosoma cruzi
por: da Silva-Gomes, Natália Lins, et al.
Publicado: (2022)

7-Aryl-7-deazapurine 3′-deoxyribonucleoside derivative as a novel lead for Chagas’ disease therapy: in vitro and in vivo pharmacology
por: Cardoso-Santos, Camila, et al.
Publicado: (2021)

Perspectives for a new drug candidate for Chagas disease therapy
por: Soeiro, Maria de Nazaré Correia
Publicado: (2022)

Norfloxacin and N-Donor Mixed-Ligand Copper(II) Complexes: Synthesis, Albumin Interaction, and Anti-Trypanosoma cruzi Activity
por: Martins, Darliane A., et al.
Publicado: (2016)

The Centennial of the Discovery of Chagas Disease: Facing the Current Challenges
por: Lannes-Vieira, Joseli, et al.
Publicado: (2010)

Antiparasitic Activity of Plumbago auriculata Extracts and Its Naphthoquinone Plumbagin against Trypanosoma cruzi
por: Peres, Raiza Brandão, et al.
Publicado: (2023)

Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones
por: de Castro, Solange L., et al.
Publicado: (2011)

Combination With Tomatidine Improves the Potency of Posaconazole Against Trypanosoma cruzi
por: Rocha-Hasler, Marianne, et al.
Publicado: (2021)

Biomakers in Chronic Chagas Cardiomyopathy
por: Rodrigues, Angela Braga, et al.
Publicado: (2022)

Important considerations regarding the widespread use of doxycycline chemoprophylaxis against sexually transmitted infections
por: Kong, Fabian Yuh Shiong, et al.
Publicado: (2023)

Intestinal permeability evaluation in patients with chronic Chagas heart failure
por: Rodrigues, Angela Braga, et al.
Publicado: (2023)

Poly-ε-Caprolactone Implants for Benznidazole Prolonged Release: An Alternative to Chagas Disease Oral Treatment
por: Mazzeti, Ana Lia, et al.
Publicado: (2023)

Chronotropic incompetence in Chagas disease: effectiveness of blended sensor (volume/minute and accelerometer)
por: Menezes Junior, Antonio da Silva, et al.
Publicado: (2015)

Impact of autologous whole blood administration upon experimental mouse models of acute Trypanosoma cruzi infection
por: Philot Pavão, Beatriz, et al.
Publicado: (2018)

Screening of Potential anti-Trypanosoma cruzi Candidates: In Vitro and In Vivo Studies
por: Soeiro, Maria de Nazaré C, et al.
Publicado: (2011)

Chemoprophylaxis in Medicine and Surgery
por: O'Grady, F. W.
Publicado: (1972)

Doxycycline for Malaria Chemoprophylaxis and Treatment: Report from the CDC Expert Meeting on Malaria Chemoprophylaxis
por: Tan, Kathrine R., et al.
Publicado: (2011)

Prevalence of transfusion-transmitted Chagas disease among multitransfused patients in Brazil
por: De Paula, Erich V, et al.
Publicado: (2008)

Chemoprophylaxis and Malaria Death Rates
por: Krause, Gérard, et al.
Publicado: (2006)

Chemoprophylaxis of Tropical Infectious Diseases
por: McBride, William J. H.
Publicado: (2010)

Nucleoside triphosphate diphosphohydrolase1 (TcNTPDase-1) gene expression is increased due to heat shock and in infective forms of Trypanosoma cruzi
por: Silva-Gomes, Natália Lins, et al.
Publicado: (2014)

Validation of the QualiPresc instrument for assessing the quality of drug prescription writing in primary health care
por: Mariz Batista, Almária, et al.
Publicado: (2022)

Phenotypic Evaluation of Nucleoside Analogues against Trypanosoma cruzi Infection: In Vitro and In Vivo Approaches
por: Fiuza, Ludmila F. de A., et al.
Publicado: (2022)

Mechanism of action of glycyrrhizin against Plasmodium falciparum
por: Soeiro, Maria de Nazaré Correia, et al.
Publicado: (2021)

Molecular Epidemiologic Source Tracking of Orally Transmitted Chagas Disease, Venezuela
por: Segovia, Maikell, et al.
Publicado: (2013)

Pre-exposure chemoprophylaxis for HIV: It is time
por: Smith, Stephen M
Publicado: (2004)

Rational malaria chemoprophylaxis – The position of primaquine
por: Baird, J. Kevin
Publicado: (2017)

Mast Cell Coupling to the Kallikrein–Kinin System Fuels Intracardiac Parasitism and Worsens Heart Pathology in Experimental Chagas Disease
por: Nascimento, Clarissa R., et al.
Publicado: (2017)

Description of an oral Chagas disease outbreak in Venezuela, including a vertically transmitted case
por: de Noya, Belkisyolé Alarcón, et al.
Publicado: (2017)

TGF-β inhibitor therapy decreases fibrosis and stimulates cardiac improvement in a pre-clinical study of chronic Chagas’ heart disease
por: Ferreira, Roberto Rodrigues, et al.
Publicado: (2019)

Vascular Growth Factor Inhibition with Bevacizumab Improves Cardiac Electrical Alterations and Fibrosis in Experimental Acute Chagas Disease
por: Nisimura, Lindice Mitie, et al.
Publicado: (2023)

In Chagas disease, transforming growth factor beta neutralization reduces Trypanosoma cruzi infection and improves cardiac performance
por: Ferreira, Roberto Rodrigues, et al.
Publicado: (2022)

CHEMOPROPHYLAXIS TO CONTROL LEPROSY AND THE PERSPECTIVE OF ITS IMPLEMENTATION IN BRAZIL: A PRIMER FOR NON-EPIDEMIOLOGISTS
por: da CUNHA, Sergio Souza, et al.
Publicado: (2015)

In vitro and in silico analysis of imatinib analogues as anti-Trypanosoma cruzi drug candidates
por: Nesic de Freitas, Luca S. F., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7ihsp3mgb7n4u19udpb7fg26h8