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Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan

Polyvinyl alcohol (PVA) is a polymeric material with good biocompatibility, excellent hydrophilicity, and a large number of hydroxyl groups. However, due to its insufficient mechanical properties and poor inhibition of bacteria, it has a lack of applications in wound dressings, stent materials, and...

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Detalles Bibliográficos
Autores principales: Guo, Linxinzheng, Hu, Kun, Wang, Haibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224062/
https://www.ncbi.nlm.nih.gov/pubmed/37242927
http://dx.doi.org/10.3390/polym15102352
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author Guo, Linxinzheng
Hu, Kun
Wang, Haibo
author_facet Guo, Linxinzheng
Hu, Kun
Wang, Haibo
author_sort Guo, Linxinzheng
collection PubMed
description Polyvinyl alcohol (PVA) is a polymeric material with good biocompatibility, excellent hydrophilicity, and a large number of hydroxyl groups. However, due to its insufficient mechanical properties and poor inhibition of bacteria, it has a lack of applications in wound dressings, stent materials, and other fields. In this study, a simple method was used to prepare composite gel materials: Ag@MXene-HACC-PVA hydrogels with a double-network structure were prepared using an acetal reaction. Due to the double cross-linked interaction, the hydrogel has good mechanical properties and is resistant to swelling. The adhesion and bacterial inhibition were enhanced due to the addition of HACC. In addition, the strain sensing properties of this conductive hydrogel were stable, and the GF (specification factor) was 1.7617 at 40–90% strain. Therefore, the dual-network hydrogel with excellent sensing properties, adhesion properties, antibacterial properties, and cytocompatibility has potential applications in biomedical materials, especially as a tissue engineering repair material.
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spelling pubmed-102240622023-05-28 Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan Guo, Linxinzheng Hu, Kun Wang, Haibo Polymers (Basel) Article Polyvinyl alcohol (PVA) is a polymeric material with good biocompatibility, excellent hydrophilicity, and a large number of hydroxyl groups. However, due to its insufficient mechanical properties and poor inhibition of bacteria, it has a lack of applications in wound dressings, stent materials, and other fields. In this study, a simple method was used to prepare composite gel materials: Ag@MXene-HACC-PVA hydrogels with a double-network structure were prepared using an acetal reaction. Due to the double cross-linked interaction, the hydrogel has good mechanical properties and is resistant to swelling. The adhesion and bacterial inhibition were enhanced due to the addition of HACC. In addition, the strain sensing properties of this conductive hydrogel were stable, and the GF (specification factor) was 1.7617 at 40–90% strain. Therefore, the dual-network hydrogel with excellent sensing properties, adhesion properties, antibacterial properties, and cytocompatibility has potential applications in biomedical materials, especially as a tissue engineering repair material. MDPI 2023-05-18 /pmc/articles/PMC10224062/ /pubmed/37242927 http://dx.doi.org/10.3390/polym15102352 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Guo, Linxinzheng
Hu, Kun
Wang, Haibo
Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan
title Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan
title_full Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan
title_fullStr Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan
title_full_unstemmed Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan
title_short Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan
title_sort antimicrobial and mechanical properties of ag@ti(3)c(2)t(x)-modified pva composite hydrogels enhanced with quaternary ammonium chitosan
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224062/
https://www.ncbi.nlm.nih.gov/pubmed/37242927
http://dx.doi.org/10.3390/polym15102352
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