Cargando…
Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan
Polyvinyl alcohol (PVA) is a polymeric material with good biocompatibility, excellent hydrophilicity, and a large number of hydroxyl groups. However, due to its insufficient mechanical properties and poor inhibition of bacteria, it has a lack of applications in wound dressings, stent materials, and...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224062/ https://www.ncbi.nlm.nih.gov/pubmed/37242927 http://dx.doi.org/10.3390/polym15102352 |
_version_ | 1785050088172683264 |
---|---|
author | Guo, Linxinzheng Hu, Kun Wang, Haibo |
author_facet | Guo, Linxinzheng Hu, Kun Wang, Haibo |
author_sort | Guo, Linxinzheng |
collection | PubMed |
description | Polyvinyl alcohol (PVA) is a polymeric material with good biocompatibility, excellent hydrophilicity, and a large number of hydroxyl groups. However, due to its insufficient mechanical properties and poor inhibition of bacteria, it has a lack of applications in wound dressings, stent materials, and other fields. In this study, a simple method was used to prepare composite gel materials: Ag@MXene-HACC-PVA hydrogels with a double-network structure were prepared using an acetal reaction. Due to the double cross-linked interaction, the hydrogel has good mechanical properties and is resistant to swelling. The adhesion and bacterial inhibition were enhanced due to the addition of HACC. In addition, the strain sensing properties of this conductive hydrogel were stable, and the GF (specification factor) was 1.7617 at 40–90% strain. Therefore, the dual-network hydrogel with excellent sensing properties, adhesion properties, antibacterial properties, and cytocompatibility has potential applications in biomedical materials, especially as a tissue engineering repair material. |
format | Online Article Text |
id | pubmed-10224062 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-102240622023-05-28 Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan Guo, Linxinzheng Hu, Kun Wang, Haibo Polymers (Basel) Article Polyvinyl alcohol (PVA) is a polymeric material with good biocompatibility, excellent hydrophilicity, and a large number of hydroxyl groups. However, due to its insufficient mechanical properties and poor inhibition of bacteria, it has a lack of applications in wound dressings, stent materials, and other fields. In this study, a simple method was used to prepare composite gel materials: Ag@MXene-HACC-PVA hydrogels with a double-network structure were prepared using an acetal reaction. Due to the double cross-linked interaction, the hydrogel has good mechanical properties and is resistant to swelling. The adhesion and bacterial inhibition were enhanced due to the addition of HACC. In addition, the strain sensing properties of this conductive hydrogel were stable, and the GF (specification factor) was 1.7617 at 40–90% strain. Therefore, the dual-network hydrogel with excellent sensing properties, adhesion properties, antibacterial properties, and cytocompatibility has potential applications in biomedical materials, especially as a tissue engineering repair material. MDPI 2023-05-18 /pmc/articles/PMC10224062/ /pubmed/37242927 http://dx.doi.org/10.3390/polym15102352 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Guo, Linxinzheng Hu, Kun Wang, Haibo Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan |
title | Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan |
title_full | Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan |
title_fullStr | Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan |
title_full_unstemmed | Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan |
title_short | Antimicrobial and Mechanical Properties of Ag@Ti(3)C(2)T(x)-Modified PVA Composite Hydrogels Enhanced with Quaternary Ammonium Chitosan |
title_sort | antimicrobial and mechanical properties of ag@ti(3)c(2)t(x)-modified pva composite hydrogels enhanced with quaternary ammonium chitosan |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224062/ https://www.ncbi.nlm.nih.gov/pubmed/37242927 http://dx.doi.org/10.3390/polym15102352 |
work_keys_str_mv | AT guolinxinzheng antimicrobialandmechanicalpropertiesofagti3c2txmodifiedpvacompositehydrogelsenhancedwithquaternaryammoniumchitosan AT hukun antimicrobialandmechanicalpropertiesofagti3c2txmodifiedpvacompositehydrogelsenhancedwithquaternaryammoniumchitosan AT wanghaibo antimicrobialandmechanicalpropertiesofagti3c2txmodifiedpvacompositehydrogelsenhancedwithquaternaryammoniumchitosan |