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Salvianolic Acid B Inhibits Ferroptosis and Apoptosis during Myocardial Ischemia/Reperfusion Injury via Decreasing the Ubiquitin-Proteasome Degradation of GPX4 and the ROS-JNK/MAPK Pathways

Myocardial ischemia/reperfusion injury (MIRI) is related to ferroptosis and apoptosis elicited by reactive oxygen species (ROS). In this research, we investigated the protective effect of salvianolic acid B (SAB) as a natural antioxidant on ferroptosis and apoptosis in the MIRI process, and discusse...

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Detalles Bibliográficos
Autores principales: Xu, Xiaojin, Mao, Chenhan, Zhang, Chengbo, Zhang, Meng, Gong, Jianbin, Wang, Xindong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224207/
https://www.ncbi.nlm.nih.gov/pubmed/37241859
http://dx.doi.org/10.3390/molecules28104117