Cargando…

Research Models to Study Ferroptosis’s Impact in Neurodegenerative Diseases

Ferroptosis is a type of regulated cell death promoted by the appearance of oxidative perturbations in the intracellular microenvironment constitutively controlled by glutathione peroxidase 4 (GPX4). It is characterized by increased production of reactive oxygen species, intracellular iron accumulat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Costa, Inês, Barbosa, Daniel José, Silva, Vera, Benfeito, Sofia, Borges, Fernanda, Remião, Fernando, Silva, Renata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224233/ https://www.ncbi.nlm.nih.gov/pubmed/37242612 http://dx.doi.org/10.3390/pharmaceutics15051369

Ejemplares similares

Fine-Tuning the Biological Profile of Multitarget Mitochondriotropic Antioxidants for Neurodegenerative Diseases
por: Chavarria, Daniel, et al.
Publicado: (2021)

Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their N-Benzylphenethylamine (NBOMe) Analogues
por: Martins, Daniel, et al.
Publicado: (2023)

Exploring the Multi-Target Performance of Mitochondriotropic Antioxidants against the Pivotal Alzheimer’s Disease Pathophysiological Hallmarks
por: Benfeito, Sofia, et al.
Publicado: (2020)

Boosting Drug Discovery for Parkinson’s: Enhancement of the Delivery of a Monoamine Oxidase-B Inhibitor by Brain-Targeted PEGylated Polycaprolactone-Based Nanoparticles
por: Pinto, Miguel, et al.
Publicado: (2019)

Ferroptosis Mechanisms Involved in Neurodegenerative Diseases
por: Reichert, Cadiele Oliana, et al.
Publicado: (2020)

Molecular Modeling and Experimental Evaluation of Non-Chiral Components of Bergamot Essential Oil with Inhibitory Activity against Human Monoamine Oxidases
por: Catalano, Raffaella, et al.
Publicado: (2022)

Nrf2 and Ferroptosis: A New Research Direction for Neurodegenerative Diseases
por: Song, Xiaohua, et al.
Publicado: (2020)

Host-Guest Interaction between Herbicide Oxadiargyl and Hydroxypropyl-β-Cyclodextrin
por: Benfeito, Sofia, et al.
Publicado: (2013)

Effects of Chlorophenoxy Herbicides and Their Main Transformation Products on DNA Damage and Acetylcholinesterase Activity
por: Benfeito, Sofia, et al.
Publicado: (2014)

Iron-responsive-like elements and neurodegenerative ferroptosis
por: Rogers, Jack T., et al.
Publicado: (2020)

Insight into the potential role of ferroptosis in neurodegenerative diseases
por: Ji, Yingying, et al.
Publicado: (2022)

Intranasal Lipid Nanoparticles Containing Bioactive Compounds Obtained from Marine Sources to Manage Neurodegenerative Diseases
por: Torres, Joana, et al.
Publicado: (2023)

In Vitro Effects of Mitochondria-Targeted Antioxidants in a Small-Cell Carcinoma of the Ovary of Hypercalcemic Type and in Type 1 and Type 2 Endometrial Cancer
por: Castelôa, Mariana, et al.
Publicado: (2022)

Mechanisms of Ferroptosis and Emerging Links to the Pathology of Neurodegenerative Diseases
por: Sun, Yiyan, et al.
Publicado: (2022)

Assessment of the Permeability of 3,4-Methylenedioxypyrovalerone (MDPV) across the Caco-2 Monolayer for Estimation of Intestinal Absorption and Enantioselectivity
por: Almeida, Ana Sofia, et al.
Publicado: (2023)

Insights into the Discovery of Novel Neuroprotective Agents: A Comparative Study between Sulfanylcinnamic Acid Derivatives and Related Phenolic Analogues
por: Chavarria, Daniel, et al.
Publicado: (2019)

Ferroptosis in Friedreich’s Ataxia: A Metal-Induced Neurodegenerative Disease
por: La Rosa, Piergiorgio, et al.
Publicado: (2020)

An In Vitro Evaluation of the Potential Neuroprotective Effects of Intranasal Lipid Nanoparticles Containing Astaxanthin Obtained from Different Sources: Comparative Studies
por: Torres, Joana, et al.
Publicado: (2023)

Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels
por: Veiga-Matos, Jéssica, et al.
Publicado: (2023)

Semi-Preparative Separation, Absolute Configuration, Stereochemical Stability and Effects on Human Neuronal Cells of MDPV Enantiomers
por: Almeida, Ana Sofia, et al.
Publicado: (2023)

Lipid Nanosystems and Serum Protein as Biomimetic Interfaces: Predicting the Biodistribution of a Caffeic Acid-Based Antioxidant
por: Fernandes, Eduarda, et al.
Publicado: (2021)

Pharmacological Inhibition of Ferroptosis as a Therapeutic Target for Neurodegenerative Diseases and Strokes
por: Wang, Yumin, et al.
Publicado: (2023)

Corrigendum to ‘A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients’. [Redox Biology 45 (2021) 102037]
por: Deus, Cláudia M., et al.
Publicado: (2021)

A mitochondria-targeted caffeic acid derivative reverts cellular and mitochondrial defects in human skin fibroblasts from male sporadic Parkinson's disease patients
por: Deus, Cláudia M., et al.
Publicado: (2021)

Fiscalin Derivatives as Potential Neuroprotective Agents
por: Barreiro, Sandra, et al.
Publicado: (2022)

Cerebroprotein hydrolysate attenuates neurodegenerative changes in Alzheimer’s mice model via ferroptosis pathway
por: Chen, Moxi, et al.
Publicado: (2023)

Synthetic Cathinones: Recent Developments, Enantioselectivity Studies and Enantioseparation Methods
por: Almeida, Ana Sofia, et al.
Publicado: (2022)

Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRP
por: Gameiro, Mariline, et al.
Publicado: (2017)

Hydroxybenzoic Acid Derivatives as Dual-Target Ligands: Mitochondriotropic Antioxidants and Cholinesterase Inhibitors
por: Oliveira, Catarina, et al.
Publicado: (2018)

Microglial Priming in Infections and Its Risk to Neurodegenerative Diseases
por: Lima, Maiara N., et al.
Publicado: (2022)

Newly Synthesized Oxygenated Xanthones as Potential P-Glycoprotein Activators: In Vitro, Ex Vivo, and In Silico Studies
por: Martins, Eva, et al.
Publicado: (2019)

Cytotoxicity and Mitochondrial Effects of Phenolic and Quinone-Based Mitochondria-Targeted and Untargeted Antioxidants on Human Neuronal and Hepatic Cell Lines: A Comparative Analysis
por: Fernandes, Carlos, et al.
Publicado: (2021)

Unwanted Exacerbation of the Immune Response in Neurodegenerative Disease: A Time to Review the Impact
por: Leite, Amanda de Oliveira Ferreira, et al.
Publicado: (2021)

Histological and toxicological evaluation, in rat, of a P-glycoprotein inducer and activator: 1-(propan-2-ylamino)-4-propoxy-9H-thioxanthen-9-one (TX5)
por: Rocha-Pereira, Carolina, et al.
Publicado: (2019)

Chiral Thioxanthones as Modulators of P-glycoprotein: Synthesis and Enantioselectivity Studies
por: Lopes, Ana, et al.
Publicado: (2018)

Antimicrobial Activity of a Library of Thioxanthones and Their Potential as Efflux Pump Inhibitors
por: Durães, Fernando, et al.
Publicado: (2021)

Bridging the gap: large animal models in neurodegenerative research
por: Eaton, S. L., et al.
Publicado: (2017)

Pixantrone, a new anticancer drug with the same old cardiac problems? An in vitro study with differentiated and non-differentiated H9c2 cells
por: Reis-Mendes, Ana, et al.
Publicado: (2018)

Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary
por: Silva, Bárbara, et al.
Publicado: (2022)

Advances in current in vitro models on neurodegenerative diseases
por: Pereira, Inês, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_8hfvv2qlr7pv5lobnue2giv60d