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Primary extrahepatic biliary neuroendocrine tumor: a case report
Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Complete sur...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224785/ https://www.ncbi.nlm.nih.gov/pubmed/37251245 http://dx.doi.org/10.1093/jscr/rjad277 |
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author | Taj, Raeda Perez, Sean Jih, Lily J Huynh, Christina Berumen, Jennifer Bouvet, Michael |
author_facet | Taj, Raeda Perez, Sean Jih, Lily J Huynh, Christina Berumen, Jennifer Bouvet, Michael |
author_sort | Taj, Raeda |
collection | PubMed |
description | Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Complete surgical resection is the gold standard treatment for these lesions. Here we present a case of a 77-year-old male with a biopsy-proven EBNET incidentally discovered during evaluation for fatty liver disease. Further workup did not show any other suspicious lesions. Resection of the tumor and multiple Roux-en-Y hepaticojejunostomy was performed. Final pathology revealed grade 1, well-differentiated neuroendocrine tumor. This is the third case reported in the literature with a confirmed preoperative EBNET diagnosis based on endoscopic biopsy results. This case highlights the feasibility of preoperative diagnosis of EBNETs and emphasizes the importance of complete surgical resection. |
format | Online Article Text |
id | pubmed-10224785 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-102247852023-05-28 Primary extrahepatic biliary neuroendocrine tumor: a case report Taj, Raeda Perez, Sean Jih, Lily J Huynh, Christina Berumen, Jennifer Bouvet, Michael J Surg Case Rep Case Report Extrahepatic biliary neuroendocrine tumors (EBNETs) are extremely rare and difficult to diagnose. The vast majority are diagnosed postoperatively on histological evaluation of surgical specimens. Workup and treatment principles are largely based on retrospective series and case reports. Complete surgical resection is the gold standard treatment for these lesions. Here we present a case of a 77-year-old male with a biopsy-proven EBNET incidentally discovered during evaluation for fatty liver disease. Further workup did not show any other suspicious lesions. Resection of the tumor and multiple Roux-en-Y hepaticojejunostomy was performed. Final pathology revealed grade 1, well-differentiated neuroendocrine tumor. This is the third case reported in the literature with a confirmed preoperative EBNET diagnosis based on endoscopic biopsy results. This case highlights the feasibility of preoperative diagnosis of EBNETs and emphasizes the importance of complete surgical resection. Oxford University Press 2023-05-27 /pmc/articles/PMC10224785/ /pubmed/37251245 http://dx.doi.org/10.1093/jscr/rjad277 Text en Published by Oxford University Press and JSCR Publishing Ltd. © The Author(s) 2023. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Case Report Taj, Raeda Perez, Sean Jih, Lily J Huynh, Christina Berumen, Jennifer Bouvet, Michael Primary extrahepatic biliary neuroendocrine tumor: a case report |
title | Primary extrahepatic biliary neuroendocrine tumor: a case report |
title_full | Primary extrahepatic biliary neuroendocrine tumor: a case report |
title_fullStr | Primary extrahepatic biliary neuroendocrine tumor: a case report |
title_full_unstemmed | Primary extrahepatic biliary neuroendocrine tumor: a case report |
title_short | Primary extrahepatic biliary neuroendocrine tumor: a case report |
title_sort | primary extrahepatic biliary neuroendocrine tumor: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224785/ https://www.ncbi.nlm.nih.gov/pubmed/37251245 http://dx.doi.org/10.1093/jscr/rjad277 |
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