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Activating the Hippo pathway by nevadensin overcomes Yap-drived resistance to sorafenib in hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is a highly malignant type of tumor that is insensitive to cytotoxic chemotherapy and often develops drug resistance. Nevadensin, a bioflavonoid, exhibits anti-cancer properties in some cancers. However, the precise underlying mechanism of nevadensin agains...
Autores principales: | Shi, Hewen, Zou, Ying, Wang, Xiaoxue, Wang, Guoli, Gao, Yijia, Yi, Fan, Xu, junqing, Yin, Yancun, Li, Defang, Li, Minjing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10224888/ https://www.ncbi.nlm.nih.gov/pubmed/37243813 http://dx.doi.org/10.1007/s12672-023-00699-y |
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